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药物反应伴嗜酸性粒细胞增多和全身症状(DRESS):临床更新和当前思维回顾。

Drug reaction with eosinophilia and systemic symptoms (DRESS): a clinical update and review of current thinking.

机构信息

Department of Dermatology, King's College Hospital, Denmark Hill, London, UK.

出版信息

Clin Exp Dermatol. 2011 Jan;36(1):6-11. doi: 10.1111/j.1365-2230.2010.03967.x.

DOI:10.1111/j.1365-2230.2010.03967.x
PMID:21143513
Abstract

Summary Drug reaction with eosinophilia and systemic symptoms (DRESS) describes a severe medication-induced adverse reaction, which has cutaneous, haematological and solid-organ features. It is one of the triad of life-threatening drug hypersensitivity dermatoses, along with acute generalized exanthematous pustulosis (AGEP) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). In this article, we discuss several controversies that surround DRESS, including problems with nomenclature and the lack of consensus in diagnostic criteria.

摘要

药物反应伴嗜酸性粒细胞增多和全身性症状(DRESS)描述了一种严重的药物诱发的不良反应,具有皮肤、血液和实体器官的特征。它是威胁生命的药物超敏性皮炎三联症之一,另外两种是急性全身性发疹性脓疱病(AGEP)和史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症(SJS/TEN)。在本文中,我们讨论了 DRESS 所涉及的几个争议,包括命名问题和诊断标准缺乏共识。

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