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骨科患者术后即刻疼痛比剖腹术后患者更剧烈,需要更多的镇痛。

Immediate postoperative pain in orthopedic patients is more intense and requires more analgesia than in post-laparotomy patients.

机构信息

Department of Anesthesia and Intensive Care Medicine, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Pain Med. 2011 Feb;12(2):308-13. doi: 10.1111/j.1526-4637.2010.01026.x. Epub 2010 Dec 10.

Abstract

OBJECTIVE

To compare the immediate postoperative pain intensity between orthopedic and general surgery patients and evaluate the extent of severe pain in each group.

DESIGN

Observational, open-label study.

SETTING

Post-anesthesia care unit (PACU) in a tertiary, university-affiliated hospital.

PATIENTS

Patients undergoing orthopedic surgery or laparotomy under general anesthesia over a one-year period.

INTERVENTIONS

Follow-up of patient self-rated pain visual analog scale (VAS, 0-10), and observation of the efficacy of the routine analgesic protocol of morphine, ketamine, and diclofenac administration in the PACU.

OUTCOME MEASURES

We followed pain scores and sorted patients according to morphine requirements during the PACU immediate postoperative stay. Patients whose pain was controlled with ≤120 µg/kg intravenous morphine were considered pain-controllable. Where this amount was insufficient to control pain (VAS ≥5/10), patients were categorized as suffering from severe pain. They were further treated with repeated doses of 1 mg morphine plus 350 µg/kg ketamine (M+K) and eventually diclofenac. PACU follow-up lasted 3 hours.

RESULTS

The overall rate of immediate severe postoperative pain within the entire cohort (3,460 patients) was 9.4%: 123 (6.6%) of laparotomy patients and 202 (12.7%) of orthopedic patients. Pain in the laparotomy patients identified as suffering from severe pain was controlled with 1.21±0.45 doses of M+K compared with 1.37±0.62 (P<0.0001) in the orthopedic counterparts. One-fifth of these laparotomy patients demanded more than one injection of M+K compared with one-third of the orthopedic subgroup (P=0.045). Twenty-seven orthopedic vs nine surgical patients (P=0.036) required diclofenac.

CONCLUSIONS

More orthopedic than laparotomy patients suffered from severe immediate postoperative pain. They required more analgesia than that dictated by existing PACU analgesia protocols. Ketamine and morphine co-administration proved effective in controlling severe postoperative pain after each type of surgery.

摘要

目的

比较骨科和普外科患者术后即刻疼痛强度,并评估每组重度疼痛的程度。

设计

观察性、开放性研究。

地点

三级大学附属医院的麻醉后护理单元(PACU)。

患者

在一年期间接受全身麻醉下骨科手术或剖腹手术的患者。

干预措施

随访患者自我评估疼痛视觉模拟量表(VAS,0-10),并观察 PACU 中常规镇痛方案(吗啡、氯胺酮和双氯芬酸钠给药)的疗效。

观察指标

我们随访疼痛评分,并根据 PACU 术后即刻住院期间吗啡需求对患者进行分类。疼痛得到控制(VAS≤120μg/kg 静脉注射吗啡)的患者被认为疼痛可控制。如果该量不足以控制疼痛(VAS≥5/10),则将患者归类为患有重度疼痛。他们进一步接受重复剂量 1mg 吗啡加 350μg/kg 氯胺酮(M+K)治疗,最终给予双氯芬酸钠。PACU 随访持续 3 小时。

结果

在整个队列(3460 例患者)中,即刻重度术后疼痛的总体发生率为 9.4%:剖腹手术患者 123 例(6.6%),骨科患者 202 例(12.7%)。被认为患有重度疼痛的剖腹手术患者,其疼痛通过 1.21±0.45 次 M+K 剂量得到控制,而骨科患者则需要 1.37±0.62 次(P<0.0001)。与骨科亚组相比,这些剖腹手术患者中有五分之一需要超过一次 M+K 注射,而骨科亚组中有三分之一(P=0.045)。与 9 例外科患者(P=0.036)相比,27 例骨科患者需要双氯芬酸钠。

结论

与剖腹手术患者相比,更多的骨科患者出现严重的即刻术后疼痛。他们需要比现有 PACU 镇痛方案规定的更多镇痛。氯胺酮和吗啡联合应用可有效控制两种手术后的重度术后疼痛。

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