Palmgren B
Department of Genetics, University of Stockholm, Sweden.
Hereditas. 1990;112(2):129-40. doi: 10.1111/j.1601-5223.1990.tb00050.x.
In tests of XXYder hybrids from two inbred lines of Drosophila melanogaster, a non-random distribution of various Yder chromosomes was found at regular X disjunction. This non-random Yder distribution was dependent on differences within the proximal X chromosome region (forked--centromere) of these particular lines, with a limited influence of the Yder,s. The Yder,s (originating from BsYy+ chromosome) showed a large influence on both level and brood pattern of secondary non-disjunction. There was no correlation between secondary non-disjunction and non-random Yder distribution, indicating different mechanisms. Cytological examination of the five Yder chromosomes disclosed no relation between the composition or configuration of the Yder,s and the observed distribution effects. Various parts of the present results show inconsistencies with either of the two existing segregation models (Grell, Novitski), suggesting that the mechanistic understanding of the meiotic process requires additional assumptions and/or alternatives.
在对来自两个黑腹果蝇近交系的XXYder杂种进行的测试中，发现在正常X染色体分离时，各种Yder染色体呈现非随机分布。这种非随机的Yder分布取决于这些特定品系近端X染色体区域（叉状——着丝粒）内的差异，Yder本身的影响有限。Yder（源自BsYy + 染色体）对二次不分离的水平和育雏模式有很大影响。二次不分离与非随机Yder分布之间没有相关性，表明存在不同的机制。对五条Yder染色体的细胞学检查表明，Yder的组成或构型与观察到的分布效应之间没有关系。本研究结果的各个部分与现有的两种分离模型（格雷尔、诺维茨基）均存在不一致，这表明对减数分裂过程的机制理解需要额外的假设和/或替代方案。
