Department of Otorhinology and Head and Neck Surgery, Haseki Research and Training Hospital, Istanbul, Turkey.
J Otolaryngol Head Neck Surg. 2010 Dec;39(6):752-6.
we evaluated eustachian tube (ET) function in patients using continuous positive airway pressure (CPAP).
cross-sectional clinical study.
tertiary referral centre.
the study included 51 patients (102 ears) with obstructive sleep apnea syndrome (OSAS), with a mean age of 51.2 years, who were using CPAP (study group) and 48 patients (96 ears) with OSAS, with a mean age of 36.0 years, who were not using CPAP (control group). ET function in the study and control groups was evaluated using the automatic Toynbee test.
the mean middle ear pressure was significantly higher in the left ear than the right ear in patients using CPAP (p = .008). The mean middle ear pressure in the right ear was significantly higher in the control group than in the group using CPAP (p = .030). There was no significant difference in functional or nonfunctional ET in the left or right ears of the patients who were or were not using CPAP.
CPAP therapy had no effect on the ET function of patients who had received CPAP therapy for a minimum of 6 months. Awareness of the effects of CPAP on the physiologic processes relevant to the upper respiratory tract will allow a better understanding and management of its side effects and may enhance patient compliance with therapy.
评估使用持续气道正压通气（CPAP）治疗的患者咽鼓管（ET）功能。
横断面临床研究。
三级转诊中心。
本研究纳入了 51 例（102 耳）阻塞性睡眠呼吸暂停综合征（OSAS）患者（平均年龄 51.2 岁，使用 CPAP 的研究组）和 48 例（96 耳）OSAS 患者（平均年龄 36.0 岁，未使用 CPAP 的对照组）。使用自动 Toynbee 试验评估研究组和对照组的 ET 功能。
使用 CPAP 的患者中，左耳的中耳平均压力明显高于右耳（p =.008）。对照组右耳的中耳平均压力明显高于使用 CPAP 的组（p =.030）。使用 CPAP 或不使用 CPAP 的患者，其左右耳的功能性或非功能性 ET 无显著差异。
CPAP 治疗至少 6 个月后，CPAP 治疗对患者的 ET 功能没有影响。了解 CPAP 对上呼吸道相关生理过程的影响，将有助于更好地理解和处理其副作用，并提高患者对治疗的依从性。
