磷酸二酯酶抑制剂4-(3-环戊氧基-4-甲氧基苯基)-2-吡咯烷酮（ZK 62711）对胃分泌及胃黏膜环磷酸腺苷的影响 - Suppr

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Effect of the phosphodiesterase inhibitor 4-(3-cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone (ZK 62711) on gastric secretion and gastric mucosal cyclic AMP.

作者信息

Puurunen J, Lücke C, Schwabe U

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1978 Aug;304(1):69-75. doi: 10.1007/BF00501379.

DOI:10.1007/BF00501379

PMID:211449

Abstract

摘要

相似文献

Effect of the phosphodiesterase inhibitor 4-(3-cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone (ZK 62711) on gastric secretion and gastric mucosal cyclic AMP.磷酸二酯酶抑制剂4-(3-环戊氧基-4-甲氧基苯基)-2-吡咯烷酮（ZK 62711）对胃分泌及胃黏膜环磷酸腺苷的影响

Naunyn Schmiedebergs Arch Pharmacol. 1978 Aug;304(1):69-75. doi: 10.1007/BF00501379.

4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone (ZK 62711): a potent inhibitor of adenosine cyclic 3',5'-monophosphate phosphodiesterases in homogenates and tissue slices from rat brain.4-（3-环戊氧基-4-甲氧基苯基）-2-吡咯烷酮（ZK 62711）：大鼠脑匀浆和组织切片中腺苷环3'，5'-单磷酸磷酸二酯酶的强效抑制剂。

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Scand J Gastroenterol. 1981;16(5):615-23. doi: 10.3109/00365528109182020.

Studies on the source of cyclic AMP in canine gastric juice.犬胃液中环磷酸腺苷来源的研究。

Dig Dis Sci. 1979 Apr;24(4):265-8. doi: 10.1007/BF01296538.

Histamine, cAMP, and activation of piglet gastric mucosa.组胺、环磷酸腺苷与仔猪胃黏膜的激活

Am J Physiol. 1982 Feb;242(2):G79-84. doi: 10.1152/ajpgi.1982.242.2.G79.

A possible role for cyclic adenosine 3',5'-monophosphate in the regulation of acid secretion in the isolated stomach of guinea-pig.环磷酸腺苷在豚鼠离体胃泌酸调节中的可能作用

Br J Pharmacol. 1977 Feb;59(2):327-32. doi: 10.1111/j.1476-5381.1977.tb07496.x.

Effects of cyclic AMP- and cyclic GMP- phosphodiesterase inhibitors on immunological release of histamine and on lung contraction.环磷酸腺苷和环磷酸鸟苷磷酸二酯酶抑制剂对组胺免疫释放及肺收缩的影响。

Br J Pharmacol. 1981 Aug;73(4):933-8. doi: 10.1111/j.1476-5381.1981.tb08748.x.

Ethanol-induced changes in gastric mucosal content of cyclic AMP and ATP in the rat.乙醇诱导的大鼠胃黏膜中环磷酸腺苷和三磷酸腺苷含量的变化。

Eur J Pharmacol. 1977 Mar 7;42(1):85-9. doi: 10.1016/0014-2999(77)90194-7.

Inhibition by cimetidine of the secretory and respiratory responses induced by theophylline and cyclic AMP in the amphibian gastric mucosa.西咪替丁对茶碱和环磷酸腺苷在两栖类胃黏膜中诱导的分泌及呼吸反应的抑制作用。

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1983;74(1):195-9. doi: 10.1016/0742-8413(83)90174-3.

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Biochem J. 1987 Jan 15;241(2):535-41. doi: 10.1042/bj2410535.

Adenosine-induced depression of synaptic transmission in the isolated olfactory cortex: receptor identification.腺苷对离体嗅皮质突触传递的抑制作用：受体鉴定

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Interactions between intracellular cyclic AMP and agonist-induced inositol phospholipid breakdown in isolated gastric mucosal cells of the rat.大鼠离体胃黏膜细胞内的环磷酸腺苷与激动剂诱导的肌醇磷脂分解之间的相互作用。

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本文引用的文献

THE ESTIMATION OF PEPSIN WITH HEMOGLOBIN.用血红蛋白对胃蛋白酶进行的测定

J Gen Physiol. 1932 Sep 20;16(1):59-63. doi: 10.1085/jgp.16.1.59.

Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。

J Biol Chem. 1951 Nov;193(1):265-75.

METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS.分离脂肪细胞的代谢。I. 激素对葡萄糖代谢和脂肪分解的影响。

J Biol Chem. 1964 Feb;239:375-80.

Influence of ethanol, caffeine and intragastric cooling on gastrin and insulin secretion in man.乙醇、咖啡因及胃内降温对人体胃泌素和胰岛素分泌的影响。

Nutr Metab. 1974;17(6):352-9. doi: 10.1159/000175559.

Sensitive determination for adenylate cyclase activity by cyclic adenosine 3',5'-monophosphate protein binding assay.通过环磷酸腺苷蛋白结合测定法灵敏测定腺苷酸环化酶活性

Naunyn Schmiedebergs Arch Pharmacol. 1974;286(1):83-96. doi: 10.1007/BF00499106.

Rat gastric mucosal cAMP following cholinergic and histamine stimulation.胆碱能和组胺刺激后大鼠胃黏膜中的环磷酸腺苷

Eur J Pharmacol. 1974 Oct;28(2):338-43. doi: 10.1016/0014-2999(74)90287-8.

Mucosal cyclic AMP and secretion in the dog stomach.犬胃黏膜中的环磷酸腺苷与分泌

Am J Physiol. 1973 Oct;225(4):893-6. doi: 10.1152/ajplegacy.1973.225.4.893.

Cyclic 3',5'-adenosine monophosphate in the rat gastric mucosa after starvation, feeding, and pentagastrin.饥饿、进食及五肽胃泌素作用后大鼠胃黏膜中的环3',5'-单磷酸腺苷

Scand J Gastroenterol. 1973;8(3):241-4.

Possible role of cyclic AMP in gastric acid secretion in rat. Activation of carbonic anhydrase.环磷酸腺苷在大鼠胃酸分泌中的可能作用。碳酸酐酶的激活。

Biochim Biophys Acta. 1973 Jun 7;311(1):90-7. doi: 10.1016/0005-2736(73)90257-5.

A comparison of the antilipolytic effects of nicotinic acid, methylisoxazole carboxylic acid, methylpyrazole carboxylic acid and insulin in isolated fat cells.烟酸、甲基异恶唑羧酸、甲基吡唑羧酸及胰岛素对分离脂肪细胞抗脂解作用的比较。

Pharmacology. 1972;8(4):280-90. doi: 10.1159/000136344.

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