Nagel-Esposito Alissa D, Kawasaki Brian, Jew Russell, Fujimoto Lane
Veterans Affairs Southern Nevada Healthcare System, Las Vegas, Nevada, USA.
Optometry. 2011 Jan;82(1):22-31. doi: 10.1016/j.optm.2010.06.013.
Lymphomas are the most common primary orbital tumor in adults 60 years of age and older. Mantle cell lymphoma (MCL) is a distinct subtype of B-cell non-Hodgkin's lymphoma. This case report describes a presentation of MCL with ocular involvement and discusses the management options.
A 63-year-old black male Vietnam veteran presented with symptoms of numbness of the right tooth and gum area with right maxillary facial pain, which he described as stabbing in nature. After extensive evaluation, the patient's symptoms were found to be caused by MCL of the right maxillary sinus invading the orbit. The lymphoma was treated successfully with a combination of high-dose corticosteroids and intensive chemotherapy and radiation therapy.
Because of the aggressive nature of MCL, early detection and diagnosis are keys to the patient's survival. Given the potential for ocular involvement, eye care professionals play an important role in the early detection and management of these patients, ensuring that they are promptly referred to a specialist, e.g., an ophthalmologist or oncologist, for appropriate testing and treatment.
淋巴瘤是60岁及以上成年人最常见的原发性眼眶肿瘤。套细胞淋巴瘤（MCL）是B细胞非霍奇金淋巴瘤的一种独特亚型。本病例报告描述了1例伴有眼部受累的MCL病例，并讨论了治疗方案。
一名63岁的黑人男性越南退伍军人，出现右牙及牙龈区域麻木伴右上颌面部疼痛症状，他描述疼痛性质为刺痛。经过全面评估，发现患者的症状是由侵犯眼眶的右上颌窦MCL引起的。该淋巴瘤通过大剂量皮质类固醇、强化化疗和放射治疗联合成功治愈。
由于MCL具有侵袭性，早期发现和诊断是患者生存的关键。鉴于存在眼部受累的可能性，眼保健专业人员在这些患者的早期发现和管理中发挥着重要作用，确保他们能及时转诊至专科医生（如眼科医生或肿瘤学家）处进行适当的检查和治疗。
