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蝶窦中的套细胞淋巴瘤导致急性双侧失明。

Mantle cell lymphoma in the sphenoid sinus showing acute bilateral blindness.

作者信息

Kanaya Yosuke, Tsunoda Atsunobu, Saigo Kanako, Tanaka Kumiko, Yoshikawa Akihisa, Kubo Satoko, Matsumoto Fumihiko

机构信息

Department of Otolaryngology-Head and Neck Surgery, Juntendo Nerima Hospital, Nerima-ku Takanodai 3-1-10, Tokyo 177-0033, Japan.

Department of Otorhinolaryngology, Juntendo University Graduate School of Medicine, Tokyo, Japan.

出版信息

Oxf Med Case Reports. 2024 Sep 2;2024(9):omae101. doi: 10.1093/omcr/omae101. eCollection 2024 Sep.

DOI:10.1093/omcr/omae101
PMID:39228826
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11367258/
Abstract

A 57-year-old man was referred to our department with a mass in the sphenoid sinus. Surgical removal of the tumor was performed. However, a testicular mass was found that showed rapid growth. He had undergone inguinal orchiectomy. Five days after the urological surgery, he noticed visual disturbances and bilateral visual loss. Ophthalmological examination revealed total blindness, and magnetic resonance imaging revealed sphenoid mass growth. The patient underwent emergent removal of the tumor, and a diagnosis of malignant lymphoma was made. A final diagnosis of mantle cell lymphoma (MCL) in the testis and sphenoid sinus was made. After receiving treatment with intravenous corticosteroids and chemotherapy for lymphoma, his left vision completely recovered. Although his right vision was lost, he returned to normal social activities. This is the first report in the literature on MCL developing in the sphenoid sinus presenting with bilateral blindness and ipsilateral recovery.

摘要

一名57岁男性因蝶窦肿物被转诊至我科。对该肿瘤进行了手术切除。然而,发现一个睾丸肿物,其生长迅速。他接受了腹股沟睾丸切除术。泌尿外科手术后五天,他注意到视觉障碍和双侧视力丧失。眼科检查显示完全失明,磁共振成像显示蝶窦肿物生长。患者接受了肿瘤的紧急切除,并诊断为恶性淋巴瘤。最终诊断为睾丸和蝶窦套细胞淋巴瘤(MCL)。在接受淋巴瘤静脉注射皮质类固醇和化疗后,他的左眼视力完全恢复。虽然他的右眼视力丧失,但他恢复了正常的社交活动。这是文献中首例关于蝶窦发生MCL并出现双侧失明及同侧视力恢复的报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf1/11367258/ad5578743cb1/omae101f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf1/11367258/cdba367848fd/omae101f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf1/11367258/e20c06d8e9c4/omae101f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf1/11367258/fbac32fceace/omae101f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf1/11367258/ad5578743cb1/omae101f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf1/11367258/cdba367848fd/omae101f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf1/11367258/e20c06d8e9c4/omae101f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf1/11367258/fbac32fceace/omae101f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf1/11367258/ad5578743cb1/omae101f4.jpg

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本文引用的文献

1
Extranodal Head and Neck Mantle Cell Lymphoma: Characteristics, Treatment, and Survival.结外头颈部套细胞淋巴瘤:特征、治疗和生存。
Ann Otol Rhinol Laryngol. 2022 Apr;131(4):412-419. doi: 10.1177/00034894211025171. Epub 2021 Jun 17.
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Two cases of numb chin syndrome diagnosed as malignant disease.两例被诊断为恶性疾病的麻木性下巴综合征病例。
Oxf Med Case Reports. 2018 Nov 5;2018(12):omy097. doi: 10.1093/omcr/omy097. eCollection 2018 Dec.
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Mantle Cell Lymphoma Presenting with Acute Bilateral Ophthalmoplegia.以急性双侧眼肌麻痹为表现的套细胞淋巴瘤
Turk J Ophthalmol. 2017 Aug;47(4):235-237. doi: 10.4274/tjo.80557. Epub 2017 Aug 15.
4
Primary non-Hodgkin lymphoma of the sphenoid sinus with visual disturbance: A report of two cases.蝶窦原发性非霍奇金淋巴瘤伴视力障碍:两例报告
Oncol Lett. 2016 Jun;11(6):4252-4254. doi: 10.3892/ol.2016.4534. Epub 2016 May 6.
5
Anatomic distribution of hematolymphoid malignancies in the head and neck: 7 years of experience with 122 patients in a single institution.头颈部血液淋巴系统恶性肿瘤的解剖分布:单一机构122例患者的7年经验
Acta Otolaryngol. 2012 Nov;132(11):1224-31. doi: 10.3109/00016489.2012.694474. Epub 2012 Oct 1.
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Mantle cell lymphoma of the maxillary sinus invading the orbit.上颌窦套细胞淋巴瘤侵犯眼眶。
Optometry. 2011 Jan;82(1):22-31. doi: 10.1016/j.optm.2010.06.013.
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Int J Oral Maxillofac Surg. 2010 Sep;39(9):869-72. doi: 10.1016/j.ijom.2010.03.029. Epub 2010 Jun 9.
8
Malignant lymphoma of the head and neck.头颈部恶性淋巴瘤。
Oral Dis. 2010 Mar;16(2):119-28. doi: 10.1111/j.1601-0825.2009.01586.x.
9
A rare case of nasal Mantle cell lymphoma.一例罕见的鼻腔套细胞淋巴瘤。
Kulak Burun Bogaz Ihtis Derg. 2010 Jan-Feb;20(1):44-7.
10
Non-Hodgkin's lymphoma of the sphenoid sinus presenting as isolated oculomotor nerve palsy.以孤立性动眼神经麻痹为表现的蝶窦非霍奇金淋巴瘤
World J Surg Oncol. 2007 Aug 3;5:86. doi: 10.1186/1477-7819-5-86.