Kuch J, Mamcarz A, Król J, Sawicki J, Braksator W
Katedry i Kliniki Kardioligii II Wydziału Lekarskiego Ak. Med., Warszawie.
Wiad Lek. 1990;43(1-2):23-7.
The effectiveness was assessed of the antiarrhythmic treatment with Palpitin in 30 patients with ischaemic heart disease (IHD). The control group comprised 15 patients with IHD and arrhythmia, treated with propranolol. In all patients ECG recording by Holter's method was done before the treatment and after 14 days of the treatment. The effectiveness of Palpitin was expressed as improvement in 66% of cases (reduction of ectopic beats by 75%), and in 40% of cases complete regression of arrhythmia was achieved. These results were slightly better than in the group treated with propranolol (improvement in 60% of cases). Palpitin during the treatment caused no increase in the manifestations of cardiac failure and produced no disturbances of atrioventricular conduction. Fairly frequently the patients complained about mucosal dryness and sporadically about dyspeptic symptoms, but these symptoms were not disturbing the course of the treatment.
评估了Palpitin对30例缺血性心脏病(IHD)患者进行抗心律失常治疗的效果。对照组包括15例患有IHD和心律失常的患者,接受普萘洛尔治疗。所有患者在治疗前和治疗14天后均采用动态心电图记录法进行心电图记录。Palpitin的有效性表现为66%的病例病情改善(异位搏动减少75%),40%的病例心律失常完全消退。这些结果略优于接受普萘洛尔治疗的组(60%的病例病情改善)。治疗期间Palpitin未导致心力衰竭表现增加,也未引起房室传导障碍。患者相当频繁地抱怨黏膜干燥,偶尔也会抱怨消化不良症状,但这些症状并未干扰治疗进程。