Penkov N, Mitkova M, Kaponov Kh, Karastatev D
Vutr Boles. 1987;26(2):54-7.
The therapeutic effect of palpitin (Gedeon Richter) was examined in an open clinical experiment with 30 patients with ectopic ventricular activity. The mean number of ventricular extra-systoles, established for one hour, was reduced from 573.7 to 149.7(p less than 0.001)--in 30.0% of the treated it completely disappeared, in 56.7% it was reduced with more than 50% and in 13.3%--there was no effect. The adverse effects are often (33.3%) but light, rarely necessitating the discontinuation of the treatment.
在一项针对30例室性异位活动患者的开放性临床实验中,对帕比汀(吉东里奇特公司生产)的治疗效果进行了研究。经测定,一小时内心室早搏的平均次数从573.7次降至149.7次(p小于0.001)——30.0%的接受治疗者早搏完全消失,56.7%的早搏次数减少超过50%,13.3%的患者无治疗效果。不良反应常见(33.3%)但较轻,很少需要中断治疗。