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[用吡二丙胺(丙吡胺)治疗异位室性心律失常]

[Treatment of ectopic ventricular activity with palpitin (disopyramide)].

作者信息

Penkov N, Mitkova M, Kaponov Kh, Karastatev D

出版信息

Vutr Boles. 1987;26(2):54-7.

PMID:2440188
Abstract

The therapeutic effect of palpitin (Gedeon Richter) was examined in an open clinical experiment with 30 patients with ectopic ventricular activity. The mean number of ventricular extra-systoles, established for one hour, was reduced from 573.7 to 149.7(p less than 0.001)--in 30.0% of the treated it completely disappeared, in 56.7% it was reduced with more than 50% and in 13.3%--there was no effect. The adverse effects are often (33.3%) but light, rarely necessitating the discontinuation of the treatment.

摘要

在一项针对30例室性异位活动患者的开放性临床实验中,对帕比汀(吉东里奇特公司生产)的治疗效果进行了研究。经测定,一小时内心室早搏的平均次数从573.7次降至149.7次(p小于0.001)——30.0%的接受治疗者早搏完全消失,56.7%的早搏次数减少超过50%,13.3%的患者无治疗效果。不良反应常见(33.3%)但较轻,很少需要中断治疗。

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