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使用分支型胸腹主动脉移植物(STAG)进行胸腹主动脉修复的手术结果。

Operative outcomes using a side-branched thoracoabdominal aortic graft (STAG) for thoraco-abdominal aortic repair.

机构信息

Division of Vascular and Endovascular Surgery, University of Perugia, Ospedale S. Maria della Misericordia, Perugia, Italy.

出版信息

Eur J Vasc Endovasc Surg. 2011 Jan;41(1):41-7. doi: 10.1016/j.ejvs.2010.10.006. Epub 2010 Dec 13.

Abstract

BACKGROUND

Pre-manufactured branched grafts now allow an endovascular approach to the repair of thoraco-abdominal aortic aneurysm (TAAA) with visceral vessels' involvement. Similar grafts have been employed in open surgery, generally as a second choice for TAAAs, which are not amenable to patch/inclusion technique for visceral vessel attachment. Results with branched grafts have not been reported in series of open TAAA repairs. The purpose of this report is to describe perioperative risks and outcomes in a consecutive series of patients with pre-manufactured side-branched thoracoabdominal aortic grafts (STAGs) for surgical TAAA repair.

METHODS

Between 1996 and 2009, pre-manufactured STAGs were used in 50 patients with TAAA that required reattachment of the visceral and renal arteries. Operative details, perioperative mortality and ischaemic complications were examined.

RESULTS

Mean age was 53 years; 18 patients were females. The cases included redo (n = 24), patients affected by genetic disorder (Marfan) (n = 20) and patients with aortic dissection (n = 27). The mean clamp time was 84.1 min. Perioperative mortality was 12.0% (6/50). Neurologic deficits occurred in 2% (1/50). Postoperative renal dysfunction was detected in 19 patients (38%).

CONCLUSION

The use of a STAG produced acceptable mortality, bowel and neurological ischaemic risks. Improved strategies to prevent renal ischaemia before and during repair of TAAA with visceral involvement are needed.

摘要

背景

预制分支移植物现在允许采用血管内方法修复涉及内脏血管的胸腹主动脉瘤(TAAA)。类似的移植物已用于开放手术中,通常作为不适合内脏血管附着的补丁/包含技术的 TAAA 的第二选择。分支移植物在开放 TAAA 修复的系列中尚未报告结果。本报告的目的是描述使用预制分支胸腹主动脉移植物(STAG)连续系列患者的围手术期风险和结果,用于外科 TAAA 修复。

方法

1996 年至 2009 年间,50 例 TAAA 患者需要重新附着内脏和肾动脉,使用预制 STAG。检查手术细节、围手术期死亡率和缺血性并发症。

结果

平均年龄为 53 岁;18 例为女性。病例包括再手术(n = 24)、遗传疾病(马凡氏综合征)患者(n = 20)和主动脉夹层患者(n = 27)。平均夹闭时间为 84.1 分钟。围手术期死亡率为 12.0%(6/50)。2%(1/50)的患者发生神经功能缺损。19 例患者(38%)术后肾功能不全。

结论

使用 STAG 产生了可接受的死亡率、肠和神经缺血风险。需要改进策略来预防内脏受累 TAAA 修复前后的肾缺血。

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