Department of Orthopaedic Surgery, Sports Injury Unit, Meir University Hospital, Kfar-Saba, Israel.
Phys Sportsmed. 2010 Dec;38(4):127-35. doi: 10.3810/psm.2010.12.1835.
Platelet-rich plasma (PRP) therapy is an emerging technology that aims to improve the process of tissue repair through local delivery of autologous bioactive agents to influence critical physiological mechanisms such as inflammation, angiogenesis, or extracellular matrix synthesis. These biological properties have prompted the therapeutic administration of PRP in orthopedics and sports medicine. Given its biocompatibility and healing properties, percutaneous injections of PRP are used in athletes to treat tendon and muscle injuries. Studies of varying levels of evidence have demonstrated the safety and beneficial effects of PRP in these applications, but standardization of the methods of plasma preparation and procedures for application is necessary for further advancements. Continued efforts to identify factors that influence the biological response to PRP treatment may yield new formulations tailored to each specific application. The growing emphasis on an evidence-based approach in the sports medicine setting demands additional research efforts before incorporating this technology in routine clinical care.
富血小板血浆 (PRP) 治疗是一种新兴技术，旨在通过局部输送自体生物活性物质来改善组织修复过程，从而影响炎症、血管生成或细胞外基质合成等关键生理机制。这些生物学特性促使 PRP 在矫形和运动医学中的治疗应用。鉴于其生物相容性和愈合特性，经皮注射 PRP 用于治疗运动员的肌腱和肌肉损伤。不同证据水平的研究表明，PRP 在这些应用中的安全性和有益效果，但需要对血浆制备方法和应用程序进行标准化，以取得进一步进展。继续努力确定影响 PRP 治疗生物学反应的因素，可能会产生针对每个特定应用的新配方。在将这项技术纳入常规临床护理之前，运动医学领域越来越强调基于证据的方法，这需要进一步的研究努力。
