Department of Urology, Bambino Gesù Children's Hospital, Rome, Italy. zaccara @ opbg.net
Fetal Diagn Ther. 2011;29(4):296-300. doi: 10.1159/000322387. Epub 2010 Dec 11.
Prenatal diagnosis of urinomas has long been established with underlying obstructive uropathy generally responsible for urinary extravasation. Because urinoma formation represents a pop-off mechanism in cases of posterior urethral valves, the number of affected males greatly exceeds the number of females. Fetal urinoma has rarely been reported without obstruction and in females it has only been described as a consequence of a complicated amniocentesis.
Three cases of fetal urinoma in female fetuses without any dilatation of the urinary tract are described. Since the fetus remained healthy, they were all conservatively managed.
Two urinomas resolved after birth and 1 exhibited significant regression. In the second case, a compressed kidney was visualized with fetal MRI. Renal function was impaired in cases 1 and 3 and absent in case 2 (the kidney was no longer visualized).
Fetal urinomas can occur even in the absence of urinary tract obstruction and in a low-pressure system as is found in female fetuses. Fetal MRI may help both visualize the ipsilateral kidney and differentiate the mass from other conditions. In a healthy fetus, fetal urinomas can be conservatively managed, but renal function after birth is often absent or impaired. Whether or not in utero aspiration may be beneficial for the preservation of renal function remains unclear.
产前诊断尿囊瘤已有很长一段时间,其根本原因通常是梗阻性尿路病变导致的尿外渗。由于尿囊瘤的形成是后尿道瓣膜病例中卸压的机制,因此受影响的男性数量大大超过女性。没有梗阻的胎儿尿囊瘤很少见,而女性的尿囊瘤仅被描述为复杂羊膜穿刺术的后果。
描述了 3 例女性胎儿无尿路扩张的胎儿尿囊瘤。由于胎儿保持健康,所有病例均保守治疗。
2 例尿囊瘤在出生后消失,1 例显著消退。在第 2 例中,胎儿 MRI 显示有被压缩的肾脏。第 1 例和第 3 例的肾功能受损,而第 2 例(肾脏不再可见)则缺失。
即使在没有尿路梗阻和女性胎儿中发现的低压系统中,胎儿尿囊瘤也可能发生。胎儿 MRI 可能有助于观察同侧肾脏,并将肿块与其他情况区分开来。在健康的胎儿中,胎儿尿囊瘤可以保守治疗,但出生后的肾功能通常缺失或受损。是否在宫内抽吸可能有利于保留肾功能尚不清楚。