Department of Cardiology, University of Alabama Birmingham, Birmingham, AL 35294-0006, USA.
Am J Ther. 2012 Sep;19(5):389-91. doi: 10.1097/MJT.0b013e3181f4b2aa.
Amiodarone is used extensively in clinical practice for the treatment of arrhythmias but is associated with a number of well-known side effects. We present 3 cases of extensive thrombosis occurring secondary to intravenous amiodarone. In cases like these, amiodarone must be stopped immediately and patients started on appropriate anticoagulation therapy. Providing education to nursing and pharmacy staff regarding the administration of IV amiodarone and the necessity of defining institutional guidelines are central to decreasing the risk of complications from using this widely available antiarrhythmic agent.
胺碘酮在临床实践中被广泛用于心律失常的治疗，但与许多已知的副作用有关。我们报告了 3 例因静脉胺碘酮而继发的广泛血栓形成的病例。在这种情况下，必须立即停止使用胺碘酮，并开始适当的抗凝治疗。向护理和药剂科工作人员提供关于静脉胺碘酮给药和制定机构指南的必要性的教育，对于降低使用这种广泛可用的抗心律失常药物的并发症风险至关重要。
