DDS Dental Centre, RAF Wittering, Peterborough, Cambs, PE8 6HB.
Br Dent J. 2010 Dec 11;209(11):E18. doi: 10.1038/sj.bdj.2010.1132.
To investigate the use of flumazenil after midazolam-induced conscious sedation.
A prospective audit was carried out in the Department of Sedation and Special Care Dentistry at Guy's Hospital, King's College, London, 2009.Subjects Patients sedated with midazolam for dental treatment.
All clinical staff completed the data capture proforma when flumazenil was administered to a patient after sedation with midazolam.
Four hundred and fifty-three patients were sedated with midazolam. Flumazenil was used in 32 cases. No cases required flumazenil for the emergency treatment of respiratory depression.
The results of the audit confirmed the safe and appropriate use of midazolam for conscious sedation within the Department of Sedation and Special Care Dentistry at Guy's Hospital and demonstrated that flumazenil use was low and in accordance with current best practice. The audit has highlighted distinct indications for the post-operative use of flumazenil in specifically selected cases. Each case should be individually considered, justified and documented within the patient's clinical record.
研究咪达唑仑诱导意识镇静后氟马西尼的应用。
2009 年，在伦敦国王学院盖伊医院镇静和特殊护理牙科系进行了一项前瞻性审核。
接受咪达唑仑镇静治疗的牙科患者。
所有临床工作人员在咪达唑仑镇静后给患者使用氟马西尼时，都填写了数据采集表。
453 例患者接受咪达唑仑镇静。32 例患者使用了氟马西尼。没有因呼吸抑制紧急治疗而需要氟马西尼的病例。
审核结果证实了咪达唑仑在盖伊医院镇静和特殊护理牙科系用于清醒镇静的安全和适当性，并表明氟马西尼的使用量较低，符合当前的最佳实践。审核突出了在特定选定病例中术后使用氟马西尼的明确适应证。每个病例都应在患者的临床记录中单独考虑、证明和记录。
