Amin Waqas, Parwani Anil V
Departments of Pathology and Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Clin Med Pathol. 2009 Sep 9;2:17-22. doi: 10.4137/cpath.s3091.
Adenomatoid tumors are responsible for 30% of all paratesticular masses. These are usually asymptomatic, slow growing masses. They are benign tumors comprising of cords and tubules of cuboidal to columnar cells with vacuolated cytoplasm and fibrous stroma. They are considered to be of mesothelial origin supported by histochemical studies and genetic analysis of Wilms tumor 1 gene expression. Excision biopsy is both diagnostic and therapeutic procedure. The main clinical consideration is accurate diagnosis preventing unnecessary orchiectomy. Diagnostic studies include serum tumor markers (negative alpha fetoprotein, beta HCG, LDH) ultrasonography (hypoechoic and homogenous appearance) and frozen section.
腺瘤样瘤占所有睾丸旁肿块的30%。这些通常是无症状、生长缓慢的肿块。它们是良性肿瘤，由立方状至柱状细胞的条索和小管组成，细胞质有空泡，伴有纤维性间质。组织化学研究和肾母细胞瘤1基因表达的遗传分析支持它们被认为起源于间皮。切除活检既是诊断性的也是治疗性的程序。主要的临床考量是准确诊断以避免不必要的睾丸切除术。诊断性检查包括血清肿瘤标志物（甲胎蛋白、β人绒毛膜促性腺激素、乳酸脱氢酶均为阴性）、超声检查（低回声且均匀外观）和冰冻切片。
