Benyi Emelie, Berner Maria, Bjernekull Inger, Boman Anders, Chrysis Dionisios, Nilsson Ola, Waehre Anne, Wehtje Henrik, Sävendahl Lars
Pediatric Endocrinology Unit and Department of Women's and Children's Health, Karolinska Institutet, 171 76 Stockholm, Sweden.
Int J Pediatr Endocrinol. 2010;2010:740629. doi: 10.1155/2010/740629. Epub 2010 Dec 2.
Objective. The aim was to determine efficacy and safety of a surgical method to reduce adult height in extremely tall adolescents. Methods. Data for all girls (n = 12) and boys (n = 9) in our center subjected to bilateral percutaneous epiphysiodesis around the knee who had reached final height were included. Final height predictions were based on hand and wrist X-rays before surgery. Results. When compared to prediction, adult height was reduced by 4.1 ± 0.7 cm in treated girls (P < .001) and 6.4 ± 0.7 cm in treated boys (P < .001) corresponding to a 33.6 ± 3.4% and 33.6 ± 4.2% reduction of remaining growth, respectively. Besides mild to moderate postoperative pain reported in 9 operated individuals, no other side effects were reported. Postoperative X-rays confirmed growth plate closure and absence of leg angulations. Conclusions. Bilateral epiphysiodesis is an effective and safe method to reduce adult height in extremely tall girls and boys.
目的。本研究旨在确定一种手术方法在极高大青少年中降低成人身高的有效性和安全性。方法。纳入了本中心所有接受双侧经皮膝关节周围骨骺阻滞术且已达到最终身高的女孩（n = 12）和男孩（n = 9）的数据。最终身高预测基于手术前的手部和腕部X线片。结果。与预测值相比，接受治疗的女孩成人身高降低了4.1±0.7厘米（P <.001），接受治疗的男孩降低了6.4±0.7厘米（P <.001），分别相当于剩余生长量减少了33.6±3.4%和33.6±4.2%。除9例接受手术者报告有轻至中度术后疼痛外，未报告其他副作用。术后X线片证实生长板闭合且无腿部成角。结论。双侧骨骺阻滞术是一种在极高大女孩和男孩中降低成人身高的有效且安全的方法。
