Fogel W A, Chmielecki C, Grałek M, Maslinski C
Department of Biogenic Amines, Polish Academy of Sciences, Lodz.
Agents Actions. 1990 Apr;30(1-2):243-6. doi: 10.1007/BF01969050.
Streptozotocin-induced diabetes in rats has been used to study the effect of insulin deficiency on histamine metabolism. There were significant increases in the amine content in the pancreas and intestine, and a significant drop in intestinal diamine oxidase (DAO) activity. The reduced DAO activity may be of clinical relevance.