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Histamine metabolism in diabetic rats.

作者信息

Fogel W A, Chmielecki C, Grałek M, Maslinski C

机构信息

Department of Biogenic Amines, Polish Academy of Sciences, Lodz.

出版信息

Agents Actions. 1990 Apr;30(1-2):243-6. doi: 10.1007/BF01969050.

Abstract

Streptozotocin-induced diabetes in rats has been used to study the effect of insulin deficiency on histamine metabolism. There were significant increases in the amine content in the pancreas and intestine, and a significant drop in intestinal diamine oxidase (DAO) activity. The reduced DAO activity may be of clinical relevance.

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