银纳米簇适体：用于蛋白质检测的固有荧光识别配体的原位生成。
Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein detection.
机构信息
MPA-CINT, Mail Stop, K771, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
出版信息
Chem Commun (Camb). 2011 Feb 28;47(8):2294-6. doi: 10.1039/c0cc03711g. Epub 2010 Dec 9.
PMID:21152540
Abstract
We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.
摘要
我们合成了一种具有内在荧光识别配体，将寡核苷酸模板化 AgNCs 的高荧光量子产率（>50%）与 DNA 适体对其靶蛋白的特异性和强结合亲和力结合起来，开发了一种用于检测特定蛋白质的新策略。
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