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一种新型荧光适体传感器用于凝血酶检测:使用聚(间苯二胺)棒作为有效的传感平台。

A novel fluorescent aptasensor for thrombin detection: using poly(m-phenylenediamine) rods as an effective sensing platform.

机构信息

State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 Jilin, China.

出版信息

Chem Commun (Camb). 2011 Apr 7;47(13):3927-9. doi: 10.1039/c1cc10402k. Epub 2011 Feb 24.

Abstract

In this communication, we develop a novel fluorescent aptasensor for thrombin detection with the use of poly(m-phenylenediamine) (PMPD) rods as an effective sensing platform. This aptasensor exhibits extraordinarily high sensitivity with a detection limit as low as 100 pM and excellent selectivity.

摘要

在本通讯中,我们开发了一种新型的荧光适体传感器,用于检测凝血酶,使用聚(间苯二胺)(PMPD)棒作为有效的传感平台。该适体传感器具有极高的灵敏度,检测限低至 100 pM,并且具有优异的选择性。

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