Camacho Santiago, Bernal Fernando, Abdo Miguel, Awad Richard A
Gastroenterology Service U-107, Endoscopy Uni, Experimental Medicine and Motility Unit, Mexico City General Hospital, México, DF, Mexico.
An Acad Bras Cienc. 2010 Dec;82(4):953-62. doi: 10.1590/s0001-37652010000400018.
The aim of this study was to analyze the data of endoscopy and symptoms in 118 Mexican patients with irritable bowel syndrome (IBS), dyspepsia, non-erosive reflux disease (NERD) and erosive esophagitis (EE). IBS criteria were fulfilling for dyspepsia patients in 47%, for NERD in 48%, and for EE patients in 48% of cases. Esophagitis was present in 42% of patients with IBS and in 45% of patients with dyspepsia. A higher prevalence of hiatus hernia was found in EE vs. NERD. Heartburn and acid eructation were associated with the presence of esophagitis; acid eructation, regurgitation and nocturnal pain with duodenitis; and heartburn and regurgitation with hiatus hernia. Males more frequently reported: mucus in feces, abdominal distension, nausea and gastritis; and women more frequently reported esophagitis and duodenitis. Patients with NERD (OR 2.54, 95% CI 1.08 to 5.99, p=0.04), tenesmus and early satiety, and men had an increase risk for reporting hard or lumpy stools. In conclusion, nearly half of the Mexican patients with NERD, EE and dyspepsia fulfill criteria for IBS. A large number of symptoms were correlated with endoscopy, which can be used to improve the indication of the endoscopy and its implementation in clinical studies.
本研究旨在分析118例患有肠易激综合征（IBS）、消化不良、非糜烂性反流病（NERD）和糜烂性食管炎（EE）的墨西哥患者的内镜检查数据和症状。IBS标准在47%的消化不良患者、48%的NERD患者和48%的EE患者中得到满足。42%的IBS患者和45%的消化不良患者存在食管炎。与NERD相比，EE患者中食管裂孔疝的患病率更高。烧心和反酸与食管炎的存在相关；反酸、反流和夜间疼痛与十二指肠炎相关；烧心和反流与食管裂孔疝相关。男性更常报告：粪便中有黏液、腹胀、恶心和胃炎；女性更常报告食管炎和十二指肠炎。NERD患者（比值比2.54，95%置信区间1.08至5.99，p = 0.04）、里急后重和早饱，男性报告硬便或块状便的风险增加。总之，近一半患有NERD、EE和消化不良的墨西哥患者符合IBS标准。大量症状与内镜检查相关，这可用于改善内镜检查的指征及其在临床研究中的应用。
