银屑病的免疫发病机制。

Immunopathogenesis of psoriasis.

作者信息

Sanchez Ana Paula Galli

机构信息

University of Sao Paulo, SP, Brazil.

出版信息

An Bras Dermatol. 2010 Sep-Oct;85(5):747-9. doi: 10.1590/s0365-05962010000500028.

DOI:10.1590/s0365-05962010000500028

PMID:21152809

Abstract

Psoriasis is a common inflammatory disease affecting 1% of the Brazilian population. Th17 and Th1cells are involved with the immunopathogenisis of psoriasis. In this article it is discussed the interaction between the innate immunity (especially dendritic cells and keratinocytes) and adaptive immunity (T lymphocytes) in the pathogenesis of psoriasis.

摘要

银屑病是一种常见的炎症性疾病，影响着1%的巴西人口。Th17细胞和Th1细胞参与了银屑病的免疫发病机制。本文讨论了先天性免疫（尤其是树突状细胞和角质形成细胞）与适应性免疫（T淋巴细胞）在银屑病发病机制中的相互作用。