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非洲爪蟾胚胎和胚胎干细胞作为发育生物学研究工具。

Xenopus embryos and ES cells as tools for studies of developmental biology.

机构信息

Department of Stem Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Honjo 2-2-1, Kumamoto, 860-0811, Japan.

出版信息

Neurochem Res. 2011 Jul;36(7):1280-5. doi: 10.1007/s11064-010-0350-9. Epub 2010 Dec 9.

DOI:10.1007/s11064-010-0350-9
PMID:21152976
Abstract

Nearly 20 years ago Professor Katsuhiko Mikoshiba led me to an exciting world of IP(3)-Ca(2+) signaling, we embarked on the role of IP(3)-Ca(2+) signaling on fertilization, early cell cycle progression, and body axis formation. I was fully enchanted by the world of basic science, particularly developmental biology. It is a great pleasure to contribute a paper to this special issue of Neurochemical Research honoring Professor Katsuhiko Mikoshiba. Many of the former lab members are now working in a wide range of fields, both inside or outside the fields of Neurochemical research. I am one of those who are working in a different field. Therefore, it seems fitting here to first write about our former work with IP3 receptor, and then introduce our recent works.

摘要

大约 20 年前,Katsuhiko Mikoshiba 教授引领我进入了一个令人兴奋的 IP(3)-Ca(2+)信号世界,我们开始研究 IP(3)-Ca(2+)信号在受精、早期细胞周期进程和体轴形成中的作用。我完全被基础科学,特别是发育生物学的世界所吸引。非常高兴能为这个纪念 Katsuhiko Mikoshiba 教授的神经化学研究特刊贡献一篇论文。许多前实验室成员现在都在神经化学研究领域内外的广泛领域工作。我就是其中之一,在一个不同的领域工作。因此,在这里首先写一些关于我们以前的 IP3 受体的工作,然后介绍我们最近的工作似乎很合适。

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Xenopus embryos and ES cells as tools for studies of developmental biology.非洲爪蟾胚胎和胚胎干细胞作为发育生物学研究工具。
Neurochem Res. 2011 Jul;36(7):1280-5. doi: 10.1007/s11064-010-0350-9. Epub 2010 Dec 9.
2
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本文引用的文献

1
Synthesized basement membranes direct the differentiation of mouse embryonic stem cells into pancreatic lineages.合成基底膜指导小鼠胚胎干细胞向胰腺谱系分化。
J Cell Sci. 2010 Aug 15;123(Pt 16):2733-42. doi: 10.1242/jcs.066886. Epub 2010 Jul 20.
2
Identification of DAF1/CD55, a novel definitive endoderm marker.新型定形内胚层标志物DAF1/CD55的鉴定
Cell Struct Funct. 2010;35(2):73-80. doi: 10.1247/csf.10004. Epub 2010 Jun 4.
3
Regulator of calcineurin 1 controls growth plasticity of adult pancreas.钙调神经磷酸酶1调节因子控制成年胰腺的生长可塑性。
Gastroenterology. 2010 Aug;139(2):609-19, 619.e1-6. doi: 10.1053/j.gastro.2010.04.050. Epub 2010 Jun 18.
4
Embryonic and adult stem cell systems in mammals: ontology and regulation.哺乳动物的胚胎和成人干细胞系统:本体论和调控。
Dev Growth Differ. 2010 Jan;52(1):115-29. doi: 10.1111/j.1440-169X.2009.01160.x.
5
Conserved origin of the ventral pancreas in chicken.鸡的腹胰具有保守起源。
Mech Dev. 2009 Oct;126(10):817-27. doi: 10.1016/j.mod.2009.07.009. Epub 2009 Aug 3.
6
Analysis of gene expressions of embryonic stem-derived Pdx1-expressing cells: implications of genes involved in pancreas differentiation.胚胎干细胞来源的表达Pdx1细胞的基因表达分析:胰腺分化相关基因的意义
Dev Growth Differ. 2009 May;51(4):463-72. doi: 10.1111/j.1440-169X.2009.01109.x.
7
Origin of pancreatic precursors in the chick embryo and the mechanism of endoderm regionalization.鸡胚胰腺前体的起源及内胚层区域化机制
Mech Dev. 2009 Jul;126(7):539-51. doi: 10.1016/j.mod.2009.03.006. Epub 2009 Mar 31.
8
FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner.成纤维细胞生长因子4(FGF4)和视黄酸以时间和浓度依赖性方式将人胚胎干细胞直接分化为表达胰腺十二指肠同源盒1(PDX1)的前肠内胚层。
PLoS One. 2009;4(3):e4794. doi: 10.1371/journal.pone.0004794. Epub 2009 Mar 11.
9
Differentiation and characterization of embryonic stem cells into three germ layers.胚胎干细胞向三个胚层的分化与特性鉴定。
Biochem Biophys Res Commun. 2009 Apr 17;381(4):694-9. doi: 10.1016/j.bbrc.2009.02.120. Epub 2009 Feb 27.
10
Generation and regeneration of cells of the liver and pancreas.肝脏和胰腺细胞的生成与再生。
Science. 2008 Dec 5;322(5907):1490-4. doi: 10.1126/science.1161431.