Department of Stem Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Honjo 2-2-1, Kumamoto, 860-0811, Japan.
Neurochem Res. 2011 Jul;36(7):1280-5. doi: 10.1007/s11064-010-0350-9. Epub 2010 Dec 9.
Nearly 20 years ago Professor Katsuhiko Mikoshiba led me to an exciting world of IP(3)-Ca(2+) signaling, we embarked on the role of IP(3)-Ca(2+) signaling on fertilization, early cell cycle progression, and body axis formation. I was fully enchanted by the world of basic science, particularly developmental biology. It is a great pleasure to contribute a paper to this special issue of Neurochemical Research honoring Professor Katsuhiko Mikoshiba. Many of the former lab members are now working in a wide range of fields, both inside or outside the fields of Neurochemical research. I am one of those who are working in a different field. Therefore, it seems fitting here to first write about our former work with IP3 receptor, and then introduce our recent works.
大约 20 年前,Katsuhiko Mikoshiba 教授引领我进入了一个令人兴奋的 IP(3)-Ca(2+)信号世界,我们开始研究 IP(3)-Ca(2+)信号在受精、早期细胞周期进程和体轴形成中的作用。我完全被基础科学,特别是发育生物学的世界所吸引。非常高兴能为这个纪念 Katsuhiko Mikoshiba 教授的神经化学研究特刊贡献一篇论文。许多前实验室成员现在都在神经化学研究领域内外的广泛领域工作。我就是其中之一,在一个不同的领域工作。因此,在这里首先写一些关于我们以前的 IP3 受体的工作,然后介绍我们最近的工作似乎很合适。