Department of Ophthalmology, People's Hospital, Peking University, 11 Xizhimen South Street, Xicheng District, 100044, Beijing, China.
Graefes Arch Clin Exp Ophthalmol. 2011 Jul;249(7):975-9. doi: 10.1007/s00417-010-1575-7. Epub 2010 Dec 14.
To describe the clinical characteristics of polypoidal choroidal vasculopathy (PCV) in a large number of Chinese patients.
This study enrolled 204 consecutive patients (246 eyes) in our department who were diagnosed as having polypoidal choroidal vasculopathy PCV. Patients underwent ophthalmologic examinations including best-corrected visual acuity (BCVA) testing, ophthalmoscopy, fundus photography, fluorescein angiography, indocyanine green angiography, and optic coherence tomography.
Mean patient age was 66.1 years and 60.3% were men. Of the cases, 79.4% were unilateral and 51.2% of BCVA was less than 35 letters. In 171 eyes (69.5%), polypoidal lesions were located in the macula area. Among them, polypoidal lesions were located in the foveal area in 29 eyes (11.8%), in the parafoveal area in 50 eyes (20.3%), and in the extrafoveal area in 88 eyes (35.8%), in both the foveal and parafoveal area in three eyes (1.2%), and in both the parafoveal and extrafoveal area in one eye (0.4%). In 37 eyes (15.0%), PCV lesions were under the temporal retinal vascular arcade; in 11 eyes (4.5%), PCV lesions were found peripapillary. PCV lesion formation was single in 88 eyes (35.8%), cluster in 145 eyes (59.0%), string in two eyes (0.8%), and branch in two eyes (0.8%). In nine eyes (3.6%), the formation of PCV lesions showed both single and cluster shape in the same eye. There were 54.5% with drusen, 44.7% with serous PED, 20.7% with hemorrhagic PED, and 39.0% with neuroretinal detachment.
The majority of Chinese PCV patients were male, unilateral, and showed macular polyps. Drusen, serous PED, hemorrhagic PED, and neuroretinal detachment on OCT were commonly seen.
描述大量中国患者中息肉样脉络膜血管病变（PCV）的临床特征。
本研究纳入了 204 例在我科确诊为息肉样脉络膜血管病变（PCV）的连续患者（246 只眼）。患者接受了眼科检查，包括最佳矫正视力（BCVA）测试、眼底镜检查、眼底照相、荧光素血管造影、吲哚青绿血管造影和光相干断层扫描。
患者平均年龄为 66.1 岁，男性占 60.3%。病例中，79.4%为单侧，51.2%的 BCVA 小于 35 个字母。在 171 只眼中（69.5%），息肉样病变位于黄斑区。其中，29 只眼（11.8%）位于黄斑中心凹，50 只眼（20.3%）位于中心凹旁，88 只眼（35.8%）位于中心凹外，3 只眼（1.2%）位于中心凹和中心凹旁，1 只眼（0.4%）位于中心凹旁和中心凹外。37 只眼（15.0%）PCV 病变位于颞侧视网膜血管弓下，11 只眼（4.5%）PCV 病变位于视盘旁。88 只眼（35.8%）PCV 病变单发，145 只眼（59.0%）PCV 病变呈簇状，2 只眼（0.8%）呈线状，2 只眼（0.8%）呈分支状。在 9 只眼（3.6%）中，同一眼 PCV 病变既有单发也有簇状。54.5%有玻璃膜疣，44.7%有浆液性 PED，20.7%有出血性 PED，39.0%有神经视网膜脱离。
大多数中国 PCV 患者为男性，单侧，表现为黄斑息肉。OCT 上常见玻璃膜疣、浆液性 PED、出血性 PED 和神经视网膜脱离。
