Bostan Bora, Erdem Mehmet, Güneş Taner, Sen Cengiz, Köseoğlu Reşit Doğan
Department of Orthopaedics and Traumatology, Gaziosmanpaşa University, Faculty of Medicine, Tokat, Turkey.
Ulus Travma Acil Cerrahi Derg. 2010 Nov;16(6):567-70.
In the present paper, we report a female patient with multiple cystic lesions of bone arising from the primary hyperparathyroidism and pathological femur and contralateral tibia fractures at the level of these cystic lesions (osteitis fibrosa cystica). The patient's history revealed that she was admitted to a medical center with vague symptoms such as sudden onset of dyspepsia, loss of appetite, myalgia, arthralgia, fatigue, and weight loss six years ago but no disease was diagnosed. Loss of appetite and loss of weight continued. She had been walking only by assisted ambulation for the last year. However, primary hyperparathyroidism was overlooked until our examination. The fractures were managed by interlocking nailing and grafting after confirming with biopsy that the fractures were due to osteitis fibrosa cystica. The fractures healed uneventfully. In conclusion, it is essential to evaluate patients with these vague symptoms with full biochemical screening and radiological examination for the early detection of the disease.
在本论文中，我们报告了一名女性患者，其患有因原发性甲状旁腺功能亢进引起的多发性骨囊性病变，并在这些囊性病变（纤维囊性骨炎）水平出现病理性股骨和对侧胫骨骨折。患者病史显示，她于六年前因消化不良、食欲不振、肌痛、关节痛、疲劳和体重减轻等模糊症状入住一家医疗中心，但未确诊任何疾病。食欲不振和体重减轻持续存在。在过去一年里，她只能借助辅助器具行走。然而，直到我们检查时才发现原发性甲状旁腺功能亢进。在通过活检确认骨折是由纤维囊性骨炎引起后，采用交锁髓内钉固定和植骨术对骨折进行了处理。骨折顺利愈合。总之，对于有这些模糊症状的患者，进行全面的生化筛查和放射学检查以早期发现疾病至关重要。
