Virology Department, Veterinary Laboratories Agency Weybridge, Addlestone, Surrey, UK.
Avian Pathol. 2010 Dec;39(6):519-24. doi: 10.1080/03079457.2010.530938.
The partial (370 nucleotides) fusion gene sequences of 55 avian paramyxovirus type 1 (APMV-1) isolates were obtained. Included were 41 published sequences, of which 16 were from strains of APMV-1 of previously determined lineages included as markers for the data analysed and 25 were from APMV-1 viruses isolated from game birds of the order Galliformes. In addition, we sequenced a further 14 game bird isolates obtained from the repository at the Veterinary Laboratories Agency. The game bird isolates had been obtained from 17 countries, and spanned four decades. Earlier studies have shown that class II APMV-1 viruses can be divided into at least 15 lineages and sub-lineages. Phylogenetic analysis revealed that the 39 game bird isolates were distributed across 12 of these sub-lineages. We conclude that no single lineage of Newcastle disease viruses appears to be prevalent in game birds, and the isolates obtained from these hosts reflected the prevailing, both geographically and temporally, viruses in poultry, pigeons or wild birds.
获得了 55 株禽副黏病毒 1 型（APMV-1）分离株的部分（370 个核苷酸）融合基因序列。其中包括 41 个已发表的序列，其中 16 个来自先前确定的 APMV-1 株系的毒株，作为分析数据的标记，25 个来自从家禽目鸟类中分离出的 APMV-1 病毒。此外，我们还对从兽医实验室局存储库中获得的另外 14 株禽类分离株进行了测序。这些禽类分离株来自 17 个国家，跨越了四个十年。早期研究表明，二类 APMV-1 病毒可分为至少 15 个株系和亚株系。系统进化分析显示，39 株禽分离株分布在这些亚株系中的 12 个中。我们的结论是，在禽类中似乎没有一种新城疫病毒株系占优势，从这些宿主中获得的分离株反映了家禽、鸽子或野生鸟类中流行的地理和时间上的病毒。
