Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
J ECT. 2010 Dec;26(4):278-9. doi: 10.1097/yct.0b013e3181da848f.
Delirious mania also known as Bell mania is a syndrome of excitement, delirium, and psychosis, of acute onset. We report 2 patients who presented with acute onset of disorientation, aggressive behavior, double incontinence, grandiose ideas, and auditory hallucinations. Results of investigations to rule out organic etiology such as computed tomographic scan of brain, cerebrospinal fluid examination, and biochemical parameters were normal. Creatine kinase levels were only moderately elevated. A provisional diagnosis of delirious mania was made, and patients were empirically started on electroconvulsive therapy (ECT) session. Delirium resolved by the second ECT session, unmasking manic symptoms, and recovered completely at the end of sixth ECT session. Prophylactic lithium was started, and both patients continue to be in remission after 1 year. Differential diagnosis of the above clinical presentation includes neuroleptic malignant syndrome and malignant catatonia. Delirious mania is clinically important owing to the potential for diagnostic confusion and good response to ECTs.
谵妄性躁狂,也称为 Bell 躁狂,是一种以兴奋、意识错乱和精神病为特征的综合征,起病急骤。我们报告了 2 例患者,他们表现为定向障碍、攻击性行为、大小便失禁、夸大观念和听觉幻觉急性发作。为排除如脑 CT 扫描、脑脊液检查和生化参数等器质性病因的检查结果均正常。肌酸激酶水平仅中度升高。暂诊断为谵妄性躁狂,并对患者进行电休克治疗(ECT)。第二次 ECT 治疗后谵妄得到缓解,出现躁狂症状,第六次 ECT 治疗结束时完全恢复。开始预防性锂治疗,两位患者在 1 年后均持续缓解。上述临床表现的鉴别诊断包括神经阻滞剂恶性综合征和恶性紧张症。由于可能导致诊断混淆和对 ECT 反应良好,谵妄性躁狂在临床上非常重要。