Vinocur P, Stine M J
Indiana Med. 1990 Jul;83(7):478-80.
The etiology of necrotizing enterocolitis (NEC) is unknown. We conducted a retrospective, case-controlled study of 23 infants hospitalized during a five-year period who developed NEC after the 11th day of life (late-onset NEC). We evaluated 58 different factors among the case and control populations to determine if there were any statistically significant differences between the two populations. Our data showed a statistically significant association between the occurrence of NEC and the use of ventilatory support (both mechanical ventilation and nasopharyngeal continuous positive airway pressure (NPCPAP)), the transpyloric (TP) feeding route and the addition of glucose polymers to feeds.
坏死性小肠结肠炎（NEC）的病因尚不清楚。我们进行了一项回顾性病例对照研究，研究对象为在五年期间住院的23例出生后11天（迟发性NEC）后发生NEC的婴儿。我们评估了病例组和对照组中的58个不同因素，以确定两组人群之间是否存在任何具有统计学意义的差异。我们的数据显示，NEC的发生与通气支持的使用（机械通气和鼻咽持续气道正压通气（NPCPAP））、经幽门（TP）喂养途径以及在喂养中添加葡萄糖聚合物之间存在统计学上的显著关联。
