Ko W, Gorovoy K
J Ophthalmic Nurs Technol. 1990 Jul-Aug;9(4):141-4.
Neurofibromatosis is an autosomal dominant disease with multiple systemic and ocular signs and features. The ocular manifestations of neurofibromatosis include a high incidence of iris hamartomas (Lisch nodules), choroidal hamartomas, and eye lid neurofibromas. Other ocular features may include conjunctival neurofibromas, prominent corneal nerves, glial tissue overlying the optic nerve, and bilateral optic atrophy due to optic glioma. Once neurofibromatosis is diagnosed, patients must have long-term ophthalmic evaluations throughout their lifetime, as this is a progressive systemic and ocular disease.
神经纤维瘤病是一种常染色体显性疾病，具有多种全身和眼部体征及特征。神经纤维瘤病的眼部表现包括虹膜错构瘤（Lisch结节）、脉络膜错构瘤和眼睑神经纤维瘤的高发病率。其他眼部特征可能包括结膜神经纤维瘤、明显的角膜神经、视神经上方的神经胶质组织以及由视神经胶质瘤导致的双侧视神经萎缩。一旦诊断出神经纤维瘤病，患者必须在其一生中接受长期的眼科评估，因为这是一种进行性的全身性和眼部疾病。
