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"睡眠剥夺"状态下的住院医师施行创伤外科手术:手术效果是否受影响?

Trauma surgery performed by "sleep deprived" residents: are outcomes affected?

机构信息

Department of Surgery, Harbor-UCLA Medical Center, Torrance, California 90509, USA.

出版信息

J Surg Educ. 2010 Nov-Dec;67(6):449-51. doi: 10.1016/j.jsurg.2010.09.003. Epub 2010 Nov 7.

DOI:10.1016/j.jsurg.2010.09.003
PMID:21156307
Abstract

BACKGROUND

The Institute of Medicine recently recommended further reductions in resident duty hours, including a 5-hour rest time for on-call residents after 16 hours of work, as a way of providing better protection for patients against fatigue-related errors, yet no data are available regarding outcomes of operations performed by surgical trainees working beyond 16 hours in the current 80-hour workweek era.

METHODS

A retrospective review of all trauma patients who required an urgent/emergent operation by the Trauma Surgery service at a Level 1 trauma center between 2003 and 2009. Operations after 10 pm were performed by residents who began their shift at 6 am, and had thus been working 16 hours. A comparison of morbidity and mortality was performed with operations performed between 6 am and 10 pm (daytime) and 10 pm and 6 am (nighttime).

RESULTS

Over the 7-year study period, 1432 trauma patients required an urgent/emergent operation. Eighty-four percent of patients were male and 71% suffered a penetrating injury. The median age for the group was 26 years. The overall complication rate was 18%, with a mortality rate of 12%. On univariate analysis there were a higher proportion of males in the nighttime group versus daytime (87% vs 82%, p = 0.007). The patients in the nighttime group were also younger (25 vs 29 years, p < 0.0001) with a lower injury severity score (ISS) (13 vs 16, p = 0.002) and had a higher proportion of penetrating injuries (81% vs 65%, p < 0.0001). The complication rate was higher in daytime (20% vs 16% for nighttime, p = 0.04), whereas the mortality rates were similar (13.5% for daytime vs 10.6%, p = 0.1). On multivariable analysis, after adjusting for age, male gender, ISS, and penetrating trauma, the time of operation was not a predictor of morbidity (odds ratio [OR] 0.97; 95% confidence interval [CI], 0.7-1.3, p = 0.9) or mortality (odds ratio1.02, 95% confidence interval, 0.7-1.6, p = 0.9).

CONCLUSIONS

Trauma surgery performed at night by residents who have worked longer than 16 hours have similar favorable outcomes compared with those performed during the day. Instituting a 5-hour rest period at night is unlikely to improve outcomes of these commonly performed operations.

摘要

背景

美国国家医学院最近建议进一步减少住院医师的工作时间,包括在工作 16 小时后给值夜班的住院医师 5 小时的休息时间,以此为患者提供更好的保护,防止因疲劳而导致错误,然而,在目前的 80 小时工作周时代,还没有关于外科住院医师在工作 16 小时后进行手术的结果的数据。

方法

对 2003 年至 2009 年期间在 1 级创伤中心创伤外科服务需要紧急/紧急手术的所有创伤患者进行回顾性分析。晚上 10 点以后的手术由早上 6 点开始轮班的住院医师进行,因此工作了 16 小时。对晚上 10 点到早上 6 点(夜间)和早上 6 点到晚上 10 点(白天)之间进行的手术的发病率和死亡率进行了比较。

结果

在 7 年的研究期间,1432 名创伤患者需要紧急/紧急手术。84%的患者为男性,71%的患者为穿透性损伤。该组的中位年龄为 26 岁。总体并发症发生率为 18%,死亡率为 12%。单因素分析显示,夜间组男性比例高于白天组(87%比 82%,p=0.007)。夜间组患者也更年轻(25 岁比 29 岁,p<0.0001),损伤严重程度评分(ISS)较低(13 比 16,p=0.002),穿透伤比例较高(81%比 65%,p<0.0001)。白天的并发症发生率更高(20%比夜间的 16%,p=0.04),而死亡率相似(白天的 13.5%比夜间的 10.6%,p=0.1)。多变量分析显示,在校正年龄、男性、ISS 和穿透性创伤后,手术时间不是发病率的预测因素(比值比[OR]0.97;95%置信区间[CI]0.7-1.3,p=0.9)或死亡率(OR1.02,95%CI0.7-1.6,p=0.9)。

结论

夜间由工作时间超过 16 小时的住院医师进行的创伤手术与白天进行的手术相比,结果相似。夜间实施 5 小时休息时间不太可能改善这些常见手术的结果。

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