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这位下肢疼痛的老年患者是否存在腰椎椎管狭窄的临床综合征?

Does this older adult with lower extremity pain have the clinical syndrome of lumbar spinal stenosis?

机构信息

Department of Physical Medicine and Rehabilitation, Harvard Medical School, and Spaulding Rehabilitation Hospital and VA Boston Healthcare System, Boston, Massachusetts 02114, USA.

出版信息

JAMA. 2010 Dec 15;304(23):2628-36. doi: 10.1001/jama.2010.1833.

Abstract

CONTEXT

The clinical syndrome of lumbar spinal stenosis (LSS) is a common diagnosis in older adults presenting with lower extremity pain.

OBJECTIVE

To systematically review the accuracy of the clinical examination for the diagnosis of the clinical syndrome of LSS.

DATA SOURCES

MEDLINE, EMBASE, and CINAHL searches of articles published from January 1966 to September 2010.

STUDY SELECTION

Studies were included if they contained adequate data on the accuracy of the history and physical examination for diagnosing the clinical syndrome of LSS, using a reference standard of expert opinion with radiographic or anatomic confirmation.

DATA EXTRACTION

Two authors independently reviewed each study to determine eligibility, extract data, and appraise levels of evidence.

DATA SYNTHESIS

Four studies evaluating 741 patients were identified. Among patients with lower extremity pain, the likelihood of the clinical syndrome of LSS was increased for individuals older than 70 years (likelihood ratio [LR], 2.0; 95% confidence interval [CI], 1.6-2.5), and was decreased for those younger than 60 years (LR, 0.40; 95% CI, 0.29-0.57). The most useful symptoms for increasing the likelihood of the clinical syndrome of LSS were having no pain when seated (LR, 7.4; 95% CI, 1.9-30), improvement of symptoms when bending forward (LR, 6.4; 95% CI, 4.1-9.9), the presence of bilateral buttock or leg pain (LR, 6.3; 95% CI, 3.1-13), and neurogenic claudication (LR, 3.7; 95% CI, 2.9-4.8). Absence of neurogenic claudication (LR, 0.23; 95% CI, 0.17-0.31) decreased the likelihood of the diagnosis. A wide-based gait (LR, 13; 95% CI, 1.9-95) and abnormal Romberg test result (LR, 4.2; 95% CI, 1.4-13) increased the likelihood of the clinical syndrome of LSS. A score of 7 or higher on a diagnostic support tool including history and examination findings increased the likelihood of the clinical syndrome of LSS (LR, 3.3; 95% CI, 2.7-4.0), while a score lower than 7 made the diagnosis much less likely (LR, 0.10; 95% CI, 0.06-0.16).

CONCLUSIONS

The diagnosis of the clinical syndrome of LSS requires the appropriate clinical picture and radiographic findings. Absence of pain when seated and improvement of symptoms when bending forward are the most useful individual findings. Combinations of findings are most useful for identifying patients who are unlikely to have the diagnosis.

摘要

背景

腰椎管狭窄症(LSS)的临床综合征是老年患者下肢疼痛的常见诊断。

目的

系统评价临床检查对 LSS 临床综合征诊断的准确性。

资料来源

1966 年 1 月至 2010 年 9 月 MEDLINE、EMBASE 和 CINAHL 对文章的检索。

研究选择

如果研究包含了对 LSS 临床综合征的病史和体检的准确性的足够数据,使用专家意见的参考标准,并进行放射学或解剖学确认,则研究被纳入。

数据提取

两名作者独立审查每项研究,以确定合格性、提取数据并评估证据水平。

数据综合

确定了四项评估 741 例患者的研究。对于下肢疼痛的患者,70 岁以上的患者 LSS 临床综合征的可能性增加(比值比[LR],2.0;95%置信区间[CI],1.6-2.5),而 60 岁以下的患者可能性降低(LR,0.40;95%CI,0.29-0.57)。对于增加 LSS 临床综合征可能性最有用的症状是坐位时无疼痛(LR,7.4;95%CI,1.9-30),前屈时症状改善(LR,6.4;95%CI,4.1-9.9),双侧臀部或腿部疼痛(LR,6.3;95%CI,3.1-13)和神经源性跛行(LR,3.7;95%CI,2.9-4.8)。无神经源性跛行(LR,0.23;95%CI,0.17-0.31)降低了诊断的可能性。宽基步态(LR,13;95%CI,1.9-95)和异常 Romberg 测试结果(LR,4.2;95%CI,1.4-13)增加了 LSS 临床综合征的可能性。诊断支持工具(包括病史和检查结果)上的评分达到 7 或更高,增加了 LSS 临床综合征的可能性(LR,3.3;95%CI,2.7-4.0),而评分低于 7 则大大降低了诊断的可能性(LR,0.10;95%CI,0.06-0.16)。

结论

LSS 临床综合征的诊断需要适当的临床和放射学表现。坐位时无疼痛和前屈时症状改善是最有用的个体发现。发现的组合对于确定不太可能做出诊断的患者最有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a326/3260477/364e44319144/nihms348020f1.jpg

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