Department of Pediatric Retina and Ocular Oncology, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, Tamil Nadu, India.
Indian J Ophthalmol. 2011 Jan-Feb;59(1):49-51. doi: 10.4103/0301-4738.73714.
Retinoblastoma is a rare intraocular tumor of childhood. Chemoreduction followed by laser or cryotherapy is the treatment of choice. Subtenon carboplatin injection is also an accepted treatment modality for vitreous seeds, along with systemic chemotherapy. Transient periocular edema, optic neuropathy and fibrosis of orbital tissues are the known side effects of subteneon carboplatin injection. We report a case of severe aseptic orbital cellulitis with necrosis and prolapse of the conjunctiva 48 h after the injection, which resolved well on only conservative management.
视网膜母细胞瘤是一种罕见的儿童眼内肿瘤。化学减瘤术联合激光或冷冻疗法是首选治疗方法。玻璃体内播散瘤采用经Tenon 囊下注射卡铂联合全身化疗也被认为是一种有效的治疗方法。经Tenon 囊下注射卡铂的已知副作用包括一过性眶周水肿、视神经病变和眼眶组织纤维化。我们报告了一例注射后 48 小时发生严重无菌性眶蜂窝织炎伴坏死和结膜脱垂的病例，仅通过保守治疗即得到良好缓解。
