Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Tamil Nadu, India.
Indian J Ophthalmol. 2011 Jan-Feb;59(1):62-4. doi: 10.4103/0301-4738.73728.
A 14-year-old girl presenting with visual loss in both eyes was diagnosed to have healed toxoplasma retinochoroiditis in the right eye with active choroidal neovascularization (CNV) secondary to toxoplasmosis in the left. She underwent combination photodynamic therapy (PDT) and intravitreal bevacizumab as primary treatment. PDT was performed as per the 'Treatment of Age-related Macular Degeneration by Photodynamic therapy' study protocol and was followed by intravitreal bevacizumab after 2 days. CNV regressed at 8 weeks of follow-up and remained stable at 8 months of follow-up. The initial visual acuity improved from 20/120 to 20/30. Combination therapy with PDT and intravitreal bevacizumab appears to be effective in the treatment of CNV secondary to toxoplasma retinochoroiditis.
一位 14 岁女孩因双眼视力丧失就诊，被诊断为右眼弓形虫性视网膜炎已愈合，左眼活动性脉络膜新生血管（CNV）继发于弓形虫病。她接受了联合光动力疗法（PDT）和玻璃体内贝伐单抗治疗作为一线治疗。PDT 按照“光动力疗法治疗年龄相关性黄斑变性”研究方案进行，随后在 2 天后进行玻璃体内贝伐单抗治疗。CNV 在 8 周的随访中消退，在 8 个月的随访中保持稳定。最初的视力从 20/120 提高到 20/30。PDT 和玻璃体内贝伐单抗联合治疗似乎对弓形虫性视网膜炎继发的 CNV 有效。
