Suppr超能文献

在Varian Clinac 6 EX和2100 CD直线加速器的Eclipse治疗计划系统中使用动态和静态多叶准直器实现电子组织补偿:可行性和剂量学研究。

Electronic tissue compensation achieved with both dynamic and static multileaf collimator in eclipse treatment planning system for Clinac 6 EX and 2100 CD Varian linear accelerators: Feasibility and dosimetric study.

作者信息

Kinhikar Rajesh A, Sharma Pramod K, Patkar Sachin, Tambe Chandrashekhar M, Deshpande Deepak D

机构信息

Department of Medical Physics, Tata Memorial Hospital, Parel, Mumbai, India.

出版信息

J Med Phys. 2007 Apr;32(2):56-9. doi: 10.4103/0971-6203.33241.

Abstract

Dynamic multileaf collimator (DMLC) and static multileaf collimator (SMLC), along with three-dimensional treatment planning system (3-D TPS), open the possibility of tissue compensation. A method using electronic tissue compensator (ETC) has been implemented in Eclipse 3-D TPS (V 7.3, Varian Medical Systems, Palo Alto, USA) at our center. The ETC was tested for head and neck conformal radiotherapy planning. The purpose of this study was to verify the feasibility of DMLC and SMLC in head and neck field irradiation for delivering homogeneous dose in the midplane at a pre-defined depth. In addition, emphasis was given to the dosimetric aspects in commissioning ETC in Eclipse. A Head and Neck Phantom (The Phantom Laboratory, USA) was used for the dosimetric verification. Planning was carried out for both DMLC and SMLC ETC plans. The dose calculated at central axis by eclipse with DMLC and SMLC was noted. This was compared with the doses measured on machine with ion chamber and thermoluminescence dosimetry (TLD). The calculated isodose curves and profiles were compared with the measured ones. The dose profiles along the two major axes from Eclipse were also compared with the profiles obtained from Amorphous Silicon (AS500) Electronic portal imaging device (EPID) on Clinac 6 EX machine. In uniform dose regions, measured dose values agreed with the calculated doses within 3%. Agreement between calculated and measured isodoses in the dose gradient zone was within 3 mm. The isodose curves and the profiles were found to be in good agreement with the measured curves and profiles. The measured and the calculated dose profiles along the two major axes were flat for both DMLC and SMLC. The dosimetric verification of ETC for both the linacs demonstrated the feasibility and the accuracy of the ETC treatment modality for achieving uniform dose distributions. Therefore, ETC can be used as a tool in head and neck treatment planning optimization for improved dose uniformity.

摘要

动态多叶准直器(DMLC)和静态多叶准直器(SMLC),连同三维治疗计划系统(3-D TPS),开启了组织补偿的可能性。我们中心已在Eclipse 3-D TPS(版本7.3,瓦里安医疗系统公司,美国帕洛阿尔托)中实施了一种使用电子组织补偿器(ETC)的方法。对ETC进行了头颈部适形放射治疗计划测试。本研究的目的是验证DMLC和SMLC在头颈部野照射中在预定深度的中平面提供均匀剂量的可行性。此外,重点关注了在Eclipse中调试ETC时的剂量学方面。使用头颈部模体(美国模体实验室)进行剂量学验证。对DMLC和SMLC的ETC计划都进行了规划。记录了通过Eclipse使用DMLC和SMLC在中心轴计算的剂量。将其与使用电离室和热释光剂量测定法(TLD)在机器上测量的剂量进行比较。将计算的等剂量曲线和轮廓与测量的进行比较。还将来自Eclipse沿两个主轴的剂量轮廓与在Clinac 6 EX机器上从非晶硅(AS500)电子射野影像装置(EPID)获得的轮廓进行比较。在均匀剂量区域,测量的剂量值与计算剂量在3%以内相符。剂量梯度区计算和测量的等剂量之间的一致性在3毫米以内。发现等剂量曲线和轮廓与测量曲线和轮廓高度吻合。对于DMLC和SMLC,沿两个主轴测量和计算的剂量轮廓都是平坦的。对两台直线加速器的ETC进行的剂量学验证证明了ETC治疗方式实现均匀剂量分布的可行性和准确性。因此,ETC可作为头颈部治疗计划优化的工具,以提高剂量均匀性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/913b/3000531/f870eaeea624/JMP-32-56-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验