Mehta Neelam, Modi Lopa, Patel Trupti, Shah Manoj
The Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India.
J Cytol. 2010 Oct;27(4):118-22. doi: 10.4103/0970-9371.73293.
Solid pseudopapillary tumor is a rare pancreatic neoplasm with uncertain to low malignant potential. This is an uncommon neoplasm with many pseudonyms, occurring predominantly in young woman under the age of thirty years.
To study the cytomorphological features of six cases of solid and pseudopapillary epithelial neoplasm of pancreas diagnosed on fine needle aspiration cytology (FNAC) in years 2005 to 2007 and its cyto-histological correlation.
Image-guided FNAs was done in these six patients preoperatively. Alcohol-fixed smears were stained with Papanicolaou stain, cytomorphological findings were evaluated and diagnosis was made. Diagnosis was later confirmed by histology in all cases.
All six cases show characteristic cytological features such as hypercellular smears with presence of abundant delicate papillary fragments, dyscohesive cells, monomorphic tumor cells with delicate folded nuclear membranes, and foamy macrophages in the background.
Preoperative correct diagnosis of solid pseudopapillary tumor of pancreas is possible on FNAC and by doing so it helps in management of this surgically curable neoplasm.
实性假乳头状肿瘤是一种罕见的胰腺肿瘤，其恶性潜能不确定至较低。这是一种有许多别名的不常见肿瘤，主要发生在30岁以下的年轻女性中。
研究2005年至2007年通过细针穿刺细胞学检查（FNAC）诊断的6例胰腺实性假乳头状上皮肿瘤的细胞形态学特征及其细胞组织学相关性。
对这6例患者术前进行图像引导下细针穿刺抽吸。酒精固定涂片用巴氏染色，评估细胞形态学结果并做出诊断。所有病例随后均经组织学确诊。
所有6例均显示出特征性的细胞学特征，如细胞涂片细胞丰富，存在大量纤细的乳头样碎片，细胞黏附性差，肿瘤细胞形态单一，核膜纤细折叠，背景中有泡沫状巨噬细胞。
通过FNAC术前正确诊断胰腺实性假乳头状肿瘤是可行的，这样有助于对这种可手术治愈的肿瘤进行管理。
