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23436例样本血液流变学分析及不同体位参考范围的建立

[Blood rheology analysis of 23436 samples and establishment of reference range by sitting and lying position].

作者信息

Li Su-zhen, Liang Jun-bing, Fan Jin-xiu, Wu Xiao-yu, Wu Wei-xian

机构信息

Department of Clinical Laboratary,Taizhou Central Hospital, Taizhou 318000, China.

出版信息

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2008 Nov;24(4):488-92.

Abstract

AIM

To establish reference range of blood theology for different gender by sitting and lying in healthy populations.

METHODS

In 31 volunteers blood were drawed in the postures of sitting and lying to measure blood rheology. Data (between July 2002 and July 2006) of 32854 samples (23436 check-up, 6553 out-patient,2865 in-patient) were collected. Differences between different postures and different gender were compared by Independ-Sample t-test with SPSS 13.0 software and each reference range of blood rheology was established.

RESULTS

In sitting and lying postures 12 parameters of blood rheology showed great significance (P < 0.01). 8 parameters such as whole blood viscosity, blood reduce viscosity, plasma viscosity, hematocrit, were decreased by 9.33% on average while posture was changed from sitting to lying. But index of erythrocyte deformability, erythrocyte electrophoresis presented inverse correlation and were increased by 6.49% on average with the same posture change.Various parameters of blood theology in different gender showed great significance (P < 0.01).

CONCLUSION

There is significant difference in various parameters of blood rheology in the posture change from sitting to lying. Reference ranges of blood theology of different postures are established which may be used to decrease the rate of misdiagnosis by 8-10 percent.

摘要

目的

建立健康人群不同性别坐位和卧位时血液流变学的参考范围。

方法

选取31名志愿者,分别在坐位和卧位抽取血液检测血液流变学指标。收集2002年7月至2006年7月间32854份样本(23436份体检样本、6553份门诊样本、2865份住院样本)的数据。运用SPSS 13.0软件通过独立样本t检验比较不同体位和不同性别的差异,并建立各血液流变学参考范围。

结果

坐位和卧位时血液流变学的12项参数差异有统计学意义(P<0.01)。从坐位变为卧位时,全血黏度、还原黏度、血浆黏度、血细胞比容等8项参数平均下降9.33%。而红细胞变形指数、红细胞电泳指数呈负相关,在相同体位变化时平均升高6.49%。不同性别的血液流变学各项参数差异有统计学意义(P<0.01)。

结论

坐位到卧位的体位变化时血液流变学各项参数有显著差异。建立了不同体位的血液流变学参考范围,可使误诊率降低8% - 10%。

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