Suppr超能文献

腹腔镜减重手术在超肥胖(BMI≥50kg/m2)患者中安全吗?一项 NSQIP 数据分析。

Are laparoscopic bariatric procedures safe in superobese (BMI ≥50 kg/m2) patients? An NSQIP data analysis.

机构信息

New York Hospital Queens, Weil Cornell Medical College, Queens, New York, USA.

出版信息

Surg Obes Relat Dis. 2011 Jul-Aug;7(4):452-8. doi: 10.1016/j.soard.2010.10.009. Epub 2010 Oct 26.

Abstract

BACKGROUND

The safety of laparoscopic bariatric procedures in superobese patients is still debatable.

METHODS

Using the American College of Surgeons National Surgical Quality Improvement Program's participant-use file, the patients who had undergone laparoscopic Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding for morbid obesity were identified. Several perioperative variables, including 30-day morbidity and mortality, were collected, and the data were compared within each procedure after dividing the patients according to the body mass index: <50 kg/m(2) (morbidly obese group and ≥50 kg/m(2) (superobese group).

RESULTS

A total of 29,323 patients who had undergone laparoscopic bariatric procedures from 2005 to 2008 were identified. Overall, compared with the morbidly obese group, the superobese group had more men (3:2), younger patients, a greater incidence of co-morbidities (e.g., hypertension and dyspnea), a significantly increased length of stay, and a greater rate of 30-day mortality (.26% versus .07%, odds ratio [OR] 4.38, P = .0001). In the gastric bypass group, the superobese group had a significantly greater incidence of postoperative complications, including superficial wound infections (2.45%, OR 1.68, P = .0001), reintubation (.61%, OR 1.97, P = .003), pulmonary embolism (.30%, OR 2.13, P = .032), myocardial infarction (.07%, P = .017), deep vein thrombosis (.49%, OR 2.06, P = .006), septic shock (.44%, OR 1.74, P = .04), and 30-day mortality (.28%, OR 2.26, P = .026). In the laparoscopic adjustable gastric banding group, the superobese group had a significantly greater incidence of postoperative complications, including superficial (1.65%, OR 2.18, P = .0013) and deep (.23%, OR 2.56, P = .035) wound infections, sepsis, septic shock and 30-day mortality (.17%, OR 13.4, P = .0219).

CONCLUSION

Laparoscopic bariatric procedures in superobese patients have been associated with significantly increased complications, including 30-day mortality, compared with morbidly obese patients. However, overall, the procedures appear to be safe, with low complication and 30-day mortality rates.

摘要

背景

腹腔镜减重手术治疗超级肥胖患者的安全性仍存在争议。

方法

利用美国外科医师学会国家手术质量改进计划的参与者使用文件,确定了接受腹腔镜 Roux-en-Y 胃旁路术和腹腔镜可调胃束带术治疗病态肥胖的患者。收集了包括 30 天发病率和死亡率在内的几项围手术期变量,并在根据 BMI 将患者分为<50kg/m²(病态肥胖组)和≥50kg/m²(超级肥胖组)后,对每个手术的患者进行比较。

结果

2005 年至 2008 年间,共确定了 29323 例接受腹腔镜减重手术的患者。总体而言,与病态肥胖组相比,超级肥胖组男性比例更高(3:2),患者更年轻,合并症(如高血压和呼吸困难)发生率更高,住院时间明显延长,30 天死亡率也更高(0.26%比 0.07%,比值比[OR] 4.38,P=0.0001)。在胃旁路组中,超级肥胖组术后并发症发生率显著增加,包括浅表伤口感染(2.45%,OR 1.68,P=0.0001)、再插管(0.61%,OR 1.97,P=0.003)、肺栓塞(0.30%,OR 2.13,P=0.032)、心肌梗死(0.07%,P=0.017)、深静脉血栓形成(0.49%,OR 2.06,P=0.006)、感染性休克(0.44%,OR 1.74,P=0.04)和 30 天死亡率(0.28%,OR 2.26,P=0.026)。在腹腔镜可调胃束带组中,超级肥胖组术后并发症发生率显著增加,包括浅表(1.65%,OR 2.18,P=0.0013)和深部(0.23%,OR 2.56,P=0.035)伤口感染、败血症、感染性休克和 30 天死亡率(0.17%,OR 13.4,P=0.0219)。

结论

与病态肥胖患者相比,腹腔镜减重手术治疗超级肥胖患者与并发症显著增加相关,包括 30 天死亡率。然而,总体而言,这些手术似乎是安全的,并发症和 30 天死亡率都很低。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验