Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University 317-1, Daemyungdong, Namku, Taegu, 705-717, Republic of Korea.
NeuroRehabilitation. 2010;27(4):367-72. doi: 10.3233/NRE-2010-0621.
We reviewed relevant diffusion tensor imaging (DTI) studies on prediction of motor outcome in hemiparetic stroke patients in order to evaluate the following objectives: characteristics of DTI for prediction of motor outcome in stroke patients, previous DTI studies, and future direction. DTI offers the unique advantage of visualization and estimation of the corticospinal tract, which is the most important neural tract for motor function. Although prediction of motor outcome is a very important topic for clinicians, only about a dozen DTI studies have been reported on this topic. These studies can be classified into two groups: 1) studies for adoption of DTI parameters as a potential marker for prediction of motor outcome in stroke patients, and 2) studies for analysis of the integrity of the corticospinal tract in prediction of motor outcome. In order to increase the predictability of motor outcome, studies according to the somatotopy and studies combined with transcranial magnetic stimulation are necessary. Other additional studies on optimal DTI scanning time for motor prediction will also be required.
我们回顾了有关弥散张量成像（DTI）在预测偏瘫中风患者运动预后方面的相关研究，以评估以下目标：DTI 预测中风患者运动预后的特征、先前的 DTI 研究和未来方向。DTI 提供了可视化和估计皮质脊髓束的独特优势，皮质脊髓束是运动功能最重要的神经束。尽管运动预后的预测是临床医生非常重要的课题，但仅有约十几项 DTI 研究涉及该主题。这些研究可分为两组：1）将 DTI 参数作为预测中风患者运动预后的潜在标志物的研究，以及 2）分析皮质脊髓束完整性以预测运动预后的研究。为了提高运动预后的可预测性，需要根据躯体定位进行研究，并结合经颅磁刺激进行研究。还需要进行其他关于用于运动预测的最佳 DTI 扫描时间的研究。
