Sato Y, Ikeda Y, Ito E, Miyano T, Kawauchi K, Yokoyama M, Kamata Y
Department of Pediatrics, School of Medicine, University of Hirosaki, Japan.
Acta Paediatr Jpn. 1990 Apr;32(2):151-4. doi: 10.1111/j.1442-200x.1990.tb00801.x.
Two patients with disseminated histiocytosis X were treated with intramuscular injections of recombinant interferon alpha A. The bone, skin and visceral lesions of these patients diminished rapidly. Significant sclerosis and recalcification of bone were observed. From our limited but positive experience, it would be justified to consider the use of interferon in patients with disseminated histiocytosis X.
两名播散性组织细胞增多症X患者接受了重组干扰素αA肌肉注射治疗。这些患者的骨骼、皮肤和内脏病变迅速减轻。观察到骨骼有明显的硬化和重新钙化。基于我们有限但积极的经验,有理由考虑对播散性组织细胞增多症X患者使用干扰素。