Lee Soon Hak, Jeon Seong Woo, Jung Min Kyu, Kim Sung Kook, Choi Gyu Seog
Soon Hak Lee, Seong Woo Jeon, Min Kyu Jung, Sung Kook Kim, Department of Internal Medicine, Kyungpook National University School of Medicine, 50 Samduk 2Ga, Chung-gu, Daegu 700-721, South Korea.
World J Gastrointest Endosc. 2009 Oct 15;1(1):56-60. doi: 10.4253/wjge.v1.i1.56.
To compare the outcomes of endoscopic resection with transanal excision in patients with early rectal cancer.
Thirty-two patients with early rectal cancer were treated by transanal excision or endoscopic resection between May 1999 and December 2007. The patients were regularly re-examined by means of colonoscopy and abdominal computed tomography after resection of the early rectal cancer. Complications, length of hospital-stay, disease recurrence and follow up outcomes were assessed.
Sixteen patients were treated by endoscopic resection and 16 patients were treated by transanal excision. No significant differences were present in the baseline characteristics. The rate of complete resection in the endoscopic resection group was 93.8%, compared to 87.5% in the transanal excision group (P = 0.544). The mean length of hospital-stay in the endoscopic resection group was 2.7 ± 1.1 d, compared to 8.9 ± 2.7 d in the transanal excision group (P = 0.001). The median follow up was 15.0 mo (range 6-99). During the follow up period, there was no case of recurrent disease in either group.
Endoscopic resection was a safe and effective method for the treatment of early rectal cancers and its outcomes were comparable to those of transanal excision procedures.
比较早期直肠癌患者内镜下切除术与经肛门切除术的治疗效果。
1999年5月至2007年12月期间，32例早期直肠癌患者接受了经肛门切除术或内镜下切除术。早期直肠癌切除术后，通过结肠镜检查和腹部计算机断层扫描对患者进行定期复查。评估并发症、住院时间、疾病复发情况和随访结果。
16例患者接受了内镜下切除术，16例患者接受了经肛门切除术。两组患者的基线特征无显著差异。内镜下切除组的完整切除率为93.8%，经肛门切除组为87.5%（P = 0.544）。内镜下切除组的平均住院时间为2.7±1.1天，经肛门切除组为8.9±2.7天（P = 0.001）。中位随访时间为15.0个月（范围6 - 99个月）。随访期间，两组均无疾病复发病例。
内镜下切除术是治疗早期直肠癌的一种安全有效的方法，其治疗效果与经肛门切除术相当。
