Köninger Jörg, Müller-Stich Beat P, Autschbach Frank, Kienle Peter, Weitz Jürgen, Büchler Markus W, Gutt Carsten N
Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Langenbecks Arch Surg. 2007 Sep;392(5):567-71. doi: 10.1007/s00423-007-0211-4. Epub 2007 Jul 18.
Low anterior resection and abdominoperineal resection with total mesorectal excision are the standard treatment in patients with low rectal cancer. Rectal resection remains a surgical intervention with considerable morbidity and long-term impairment of quality of life. Local excision of low rectal cancer is regarded as an alternative to radical surgery; however, occurrence of lymph node metastasis even in patients with highly differentiated early-stage rectal cancer may be underestimated.
In two patients with T1 rectal cancer, minimal-invasive partial excision of the mesorectum was performed after transanal excision of the tumor. The postoperative course was uneventful in both patients. Patients left the hospital on the fourth and fifth postoperative day without any complaints. In one patient, histo-pathological workup revealed a lymph node metastasis in the specimen.
The technique of "Endoscopic posterior mesorectal resection" represents an interesting option in the surgical treatment of rectal cancer, as it allows for the first time an organ preserving resection of local lymph nodes in the small pelvis. It may evolve as an efficient new staging procedure to identify patients with metastatic disease who may benefit from multimodal treatment or extended surgery.
低位前切除术和腹会阴联合切除术加全直肠系膜切除术是低位直肠癌患者的标准治疗方法。直肠切除术仍然是一种具有相当高发病率和长期生活质量受损的外科干预措施。低位直肠癌的局部切除术被视为根治性手术的替代方法;然而,即使在高分化早期直肠癌患者中,淋巴结转移的发生率可能也被低估了。
在两名T1期直肠癌患者中,经肛门切除肿瘤后进行了微创直肠系膜部分切除术。两名患者术后过程均顺利。患者分别在术后第4天和第5天出院,无任何不适主诉。在一名患者中,组织病理学检查显示标本中有淋巴结转移。
“内镜下直肠后系膜切除术”技术是直肠癌外科治疗中一个有趣的选择,因为它首次允许在小骨盆中进行保留器官的局部淋巴结切除术。它可能会发展成为一种有效的新分期程序,以识别可能从多模式治疗或扩大手术中获益的转移性疾病患者。