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直肠出血作为AL型淀粉样变性和多发性骨髓瘤的首发症状。

Rectal bleeding as a presenting symptom of AL amyloidosis and multiple myeloma.

作者信息

Maza Itay, Vlodavsky Evgene, Eliakim Rami A

机构信息

Itay Maza, Rami A Eliakim, Department of Gastroenterology, Rambam Health Care Campus, Technion School of Medicine, Haifa 31096, Israel.

出版信息

World J Gastrointest Endosc. 2010 Jan 16;2(1):44-6. doi: 10.4253/wjge.v2.i1.44.

DOI:10.4253/wjge.v2.i1.44
PMID:21160679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2999078/
Abstract

Amyloidosis of the gastrointestinal tract is a rare disease that presents with common, nonspecific signs and symptoms. It may affect any part of the gastrointestinal tract from mouth to anus. The clinical and endoscopic features are diverse and may mimic other diseases, such as inflammatory bowel disease, malignancy, ischemic colitis and, at times, collagenous colitis. We describe an uncommon case of rectal bleeding and anemia with polypoid lesions and ulcerations in the colon, as the presenting symptom of AL amyloidosis and light chain multiple myeloma.

摘要

胃肠道淀粉样变性是一种罕见疾病,表现为常见的非特异性体征和症状。它可能影响从口腔到肛门的胃肠道任何部位。其临床和内镜特征多样,可能与其他疾病相似,如炎症性肠病、恶性肿瘤、缺血性结肠炎,有时还与胶原性结肠炎相似。我们描述了一例罕见病例,以直肠出血、贫血以及结肠息肉样病变和溃疡为表现症状,诊断为AL型淀粉样变性和轻链多发性骨髓瘤。

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引用本文的文献

1
Gastrointestinal bleeding as an initial manifestation in asymptomatic multiple myeloma: A case report and review of the literature.胃肠道出血作为无症状多发性骨髓瘤的首发表现:一例病例报告及文献复习
Oncol Lett. 2013 Jan;5(1):218-220. doi: 10.3892/ol.2012.945. Epub 2012 Oct 1.
2
A rare cause of lower GI bleeding.下消化道出血的一种罕见病因。
BMJ Case Rep. 2012 Sep 7;2012:bcr0320126086. doi: 10.1136/bcr.03.2012.6086.

本文引用的文献

1
Gastrointestinal amyloidosis presenting with multiple episodes of gastrointestinal bleeding.
Cardiovasc Intervent Radiol. 2009 May;32(3):577-80. doi: 10.1007/s00270-008-9429-y. Epub 2008 Sep 17.
2
Amyloidosis presenting as lower gastrointestinal hemorrhage.表现为下消化道出血的淀粉样变性病。
WMJ. 2008 Feb;107(1):40-3.
3
Review article: gastrointestinal amyloidosis - clinical features, diagnosis and therapy.综述文章:胃肠道淀粉样变性——临床特征、诊断与治疗
Aliment Pharmacol Ther. 2008 Jun 1;27(11):1006-16. doi: 10.1111/j.1365-2036.2008.03682.x. Epub 2008 Mar 17.
4
Gastrointestinal manifestations of amyloidosis.淀粉样变性的胃肠道表现。
Am J Gastroenterol. 2008 Mar;103(3):776-87. doi: 10.1111/j.1572-0241.2007.01669.x. Epub 2007 Dec 12.
5
Clinical recognition of Al type amyloidosis of the luminal gastrointestinal tract.腔内胃肠道AL型淀粉样变性的临床识别
Clin Gastroenterol Hepatol. 2007 May;5(5):582-8. doi: 10.1016/j.cgh.2007.02.038. Epub 2007 Apr 11.