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Rectal bleeding as a presenting symptom of AL amyloidosis and multiple myeloma.直肠出血作为AL型淀粉样变性和多发性骨髓瘤的首发症状。
World J Gastrointest Endosc. 2010 Jan 16;2(1):44-6. doi: 10.4253/wjge.v2.i1.44.
2
Amyloidosis presenting as lower gastrointestinal hemorrhage.表现为下消化道出血的淀粉样变性病。
WMJ. 2008 Feb;107(1):40-3.
3
Review article: gastrointestinal amyloidosis - clinical features, diagnosis and therapy.综述文章:胃肠道淀粉样变性——临床特征、诊断与治疗
Aliment Pharmacol Ther. 2008 Jun 1;27(11):1006-16. doi: 10.1111/j.1365-2036.2008.03682.x. Epub 2008 Mar 17.
4
Gastrointestinal manifestations of amyloidosis.淀粉样变性的胃肠道表现。
Am J Gastroenterol. 2008 Mar;103(3):776-87. doi: 10.1111/j.1572-0241.2007.01669.x. Epub 2007 Dec 12.
5
Clinical recognition of Al type amyloidosis of the luminal gastrointestinal tract.腔内胃肠道AL型淀粉样变性的临床识别
Clin Gastroenterol Hepatol. 2007 May;5(5):582-8. doi: 10.1016/j.cgh.2007.02.038. Epub 2007 Apr 11.
6
Diagnostic and therapeutic approach of systemic amyloidosis.系统性淀粉样变性的诊断与治疗方法。
Neth J Med. 2004 Apr;62(4):121-8.

下消化道出血的一种罕见病因。

A rare cause of lower GI bleeding.

作者信息

Waleed Mohammad, Ali A Mohamed, Saraj Othman, Babu Sathish, Morgan Russell

机构信息

Department of Gastroenterology, Scarborough General Hospital, North Yorkshire, UK.

出版信息

BMJ Case Rep. 2012 Sep 7;2012:bcr0320126086. doi: 10.1136/bcr.03.2012.6086.

DOI:10.1136/bcr.03.2012.6086
PMID:22962379
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3448767/
Abstract

The authors present a rare case of lower gastrointestinal (GI) bleed due to GI amyloidosis secondary to multiple myeloma. A 79-year-old lady who presented with bloody diarrhoea for 4 weeks. Flexible sigmoidoscopy showed slight oedematous mucosa extending up to the sigmoid colon. CT abdomen showed lytic lesions in the vertebral bodies. 24 h protein analysis and serum electrophoresis suggestive of multiple myeloma, which was confirmed with bone marrow biopsy, revealed plasma cell myeloma.

摘要

作者报告了一例罕见的因多发性骨髓瘤继发胃肠道淀粉样变性导致的下消化道出血病例。一名79岁女性,出现便血4周。乙状结肠镜检查显示黏膜轻度水肿,向上延伸至乙状结肠。腹部CT显示椎体有溶骨性病变。24小时蛋白分析和血清电泳提示多发性骨髓瘤,骨髓活检确诊为浆细胞骨髓瘤。