Waleed Mohammad, Ali A Mohamed, Saraj Othman, Babu Sathish, Morgan Russell
Department of Gastroenterology, Scarborough General Hospital, North Yorkshire, UK.
BMJ Case Rep. 2012 Sep 7;2012:bcr0320126086. doi: 10.1136/bcr.03.2012.6086.
The authors present a rare case of lower gastrointestinal (GI) bleed due to GI amyloidosis secondary to multiple myeloma. A 79-year-old lady who presented with bloody diarrhoea for 4 weeks. Flexible sigmoidoscopy showed slight oedematous mucosa extending up to the sigmoid colon. CT abdomen showed lytic lesions in the vertebral bodies. 24 h protein analysis and serum electrophoresis suggestive of multiple myeloma, which was confirmed with bone marrow biopsy, revealed plasma cell myeloma.
作者报告了一例罕见的因多发性骨髓瘤继发胃肠道淀粉样变性导致的下消化道出血病例。一名79岁女性,出现便血4周。乙状结肠镜检查显示黏膜轻度水肿,向上延伸至乙状结肠。腹部CT显示椎体有溶骨性病变。24小时蛋白分析和血清电泳提示多发性骨髓瘤,骨髓活检确诊为浆细胞骨髓瘤。