Ignee Andre, Straub Bernd, Schuessler Gudrun, Dietrich Christoph Frank
Andre Ignee, Gudrun Schuessler, Christoph Frank Dietrich, 2nd Department of Internal Medicine, Caritas Krankenhaus, Uhlandstrasse 7, 97980 Bad Mergentheim, Germany.
World J Radiol. 2010 Jan 28;2(1):15-31. doi: 10.4329/wjr.v2.i1.15.
Contrast enhanced ultrasound (CEUS) has gained clinical importance over the last years for the characterization of hepatic masses. Its role in extrahepatic indications has been investigated repeatedly but has been less comprehensively studied. Currently more than 50% of renal masses are incidentally diagnosed, mostly by B-mode ultrasound. The method of choice for characterization of renal lesions is contrast enhanced computed tomography (CECT). In the case of cystic lesions CECT refers to the Bosniak classification for cystic lesions to assess the risk of malignant behavior. The majority of masses are renal cell carcinoma, but the exact proportion is controversial. Disadvantages of CECT are a significant risk for patients with impaired renal function, allergic reactions and hyperthyroidism due to iodinated contrast agents. Several studies concerning CEUS for the characterization of both solid and cystic renal lesions have been published, but prospective multicenter studies are missing, the presented data being mainly descriptive. The aim of the this manuscript is to review the current literature for CEUS in renal masses, to summarize the available data and focus on possible concepts for studies in the future.
在过去几年中，超声造影（CEUS）在肝脏肿块的特征性诊断方面已具有临床重要性。其在肝外适应症中的作用已被反复研究，但研究不够全面。目前，超过50%的肾肿块是偶然发现的，大多通过B超诊断。肾病变特征性诊断的首选方法是增强计算机断层扫描（CECT）。对于囊性病变，CECT采用博斯尼亚克囊性病变分类法来评估恶性行为风险。大多数肿块为肾细胞癌，但确切比例存在争议。CECT的缺点是，对于肾功能受损患者、碘造影剂引起的过敏反应患者和甲状腺功能亢进患者存在重大风险。已经发表了几项关于CEUS用于实性和囊性肾病变特征性诊断的研究，但缺乏前瞻性多中心研究，所呈现的数据主要是描述性的。本手稿的目的是回顾当前关于CEUS在肾肿块中的文献，总结现有数据，并关注未来研究的可能概念。
