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[术后医源性黄疸]

[Postoperative medical icterus].

作者信息

Cerf M

出版信息

Sem Hop. 1978 Jun;54(17-20):625-9.

PMID:211610
Abstract

The onset of jaundice following a surgical operation sometimes raises difficult problems. It is rarely due to hemolysis, infective hepatitis or decomposated cirrhosis of the liver. One should seek as a routine hepatitis due to halotane. However the most frequent cause is "benign postoperative cholestasis". This variety of jaundice presents in the form of an icterus due to conjugated bilirubine with often a large increase in alkaline phosphatase levels. The ocurse is variable. Almost always due to severe surgical or septic trauma, accompanied by shock and/or anoxia, it raises difficult diagnostic problems. The clinical and physiopathological aspects of benign postoperative cholestasis are recalled. One should remember, above all, that this is not an autonomous clinical entity but the sign of local or general complications which should be sought carefully.

摘要

外科手术后出现黄疸有时会引发难题。其很少由溶血、感染性肝炎或肝分解性肝硬化引起。通常应排查因氟烷导致的肝炎。然而,最常见的原因是“良性术后胆汁淤积”。这种黄疸表现为结合胆红素所致的黄疸,碱性磷酸酶水平常常大幅升高。病程多变。几乎总是由严重的外科手术或脓毒症创伤引起,伴有休克和/或缺氧,这引发了诊断难题。文中回顾了良性术后胆汁淤积的临床和生理病理方面。尤其要记住,这并非一种独立的临床实体,而是局部或全身并发症的体征,应仔细查找。

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