神经成像中的动脉自旋标记
Arterial spin labeling in neuroimaging.
作者信息
Petcharunpaisan Sasitorn, Ramalho Joana, Castillo Mauricio
机构信息
Sasitorn Petcharunpaisan, Division of Neuroradiology, University of North Carolina at Chapel Hill, Room 3326, Old Infirmary Building, Manning Drive, Chapel Hill, NC 27599-7510, United States.
出版信息
World J Radiol. 2010 Oct 28;2(10):384-98. doi: 10.4329/wjr.v2.i10.384.
Abstract
Arterial spin labeling (ASL) is a magnetic resonance imaging technique for measuring tissue perfusion using a freely diffusible intrinsic tracer. As compared with other perfusion techniques, ASL offers several advantages and is now available for routine clinical practice in many institutions. Its noninvasive nature and ability to quantitatively measure tissue perfusion make ASL ideal for research and clinical studies. Recent technical advances have increased its sensitivity and also extended its potential applications. This review focuses on some basic knowledge of ASL perfusion, emerging techniques and clinical applications in neuroimaging.
摘要
动脉自旋标记（ASL）是一种磁共振成像技术，用于使用可自由扩散的内源性示踪剂测量组织灌注。与其他灌注技术相比，ASL具有多个优点，现在许多机构都可用于常规临床实践。其非侵入性本质以及定量测量组织灌注的能力使ASL成为研究和临床研究的理想选择。最近的技术进步提高了其灵敏度，并扩展了其潜在应用。本综述重点介绍ASL灌注的一些基础知识、新兴技术以及在神经成像中的临床应用。
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