Institute of Population Research, Peking University, Beijing 100871, P.R. China. [corrected]
Int J Environ Health Res. 2010 Dec;20(6):439-50. doi: 10.1080/09603123.2010.491854.
Shanxi province in northern China has one of the highest reported prevalence rates of neural tube defects (NTDs) in the world. The current study selected Heshun, the county with the highest rate of NTDs in Shanxi, as a study area and tested whether residence in a coal mining area was a contributing factor. A NTD cluster was detected in an area within 6 km of the coal mines for almost every year during 1998-2005. Poisson regression analysis revealed that there may be an association between production in coal mines and prevalence of NTDs in coal mine areas. Future work identifying factors independently correlated with NTDs in coal mining regions may provide further insights into the health effects of coal mines on NTDs.
中国北方的山西省是世界上报导的神经管缺陷（NTDs）发病率最高的地区之一。本研究选择山西省 NTDs 发病率最高的和顺作为研究区域，并检测居住在矿区是否是一个促成因素。在 1998 年至 2005 年期间，几乎每年都在煤矿 6 公里范围内发现了一个 NTD 聚集区。泊松回归分析显示，煤矿的生产可能与煤矿地区 NTD 的患病率之间存在关联。未来在煤矿地区确定与 NTD 独立相关的因素的工作可能会进一步深入了解煤矿对 NTD 的健康影响。
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