Zhang Shu-cheng, Wang Wei-lin, Qu Ri-bin, Su Peng-jun, Zhang Shi-wei, Zhang Hao-ran, Tan Shi-yong, Chen Xiao-juan, Zhang Wei, Ai De-bin, Wu Hai-tao, Gong Liang-cai, Wang Jian-li, He Yan, Wan Chao, Dong Guang-hui
Department of Pediatric Surgery, Shengjing Hospital, China Medical University, Shenyang 110004, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2010 Jul;31(7):751-4.
Functional constipation (FC) is a common complaint in childhood but the prevalence still remains unclear, the aim of this study was to explore the prevalence of FC in childhood in the northern parts of China.
A screening program on FC in childhood was carried out in 5 northern cities (Beijing, Tianjin, Shenyang, Changchun, Harbin) of China according to symptoms under the Rome III criteria. Random clustered sampling of the inhabitants was carried out under stratification of cities, geographic zones, schools or nurseries. Sample size of each area was in proportion to the population of the area. The range of age was 4-14. All subjects under study were requested to fill in a questionnaire distributed by the teachers. The screening program was carried out immediately after a section survey was completed. All together, 20 000 questionnaires were distributed with 19 638 retrievals. According to the result of the screening, a small number of patients who met the criteria were further selected to undergo a detailed clinical examination in the hospital including laboratory examination, colonic transit time, defecography or/and barium enema, electromyologram and anorectal manometry to exclude organic disease of the colon. Simultaneously, a detailed questionnaire was requested to fill under the assistance of trained doctors or medical students. Prevalence of FC of the population was adjusted by the rate of correct diagnosis from the detailed study.
The adjusted point prevalence of FC in 5 northern cities of China according to Rome III criteria was 4.73% with higher prevalence rate of FC seen in the Beijing area (5.02%) than in other cities (4.82%, 4.76%, 4.27%, 4.40%, with P < 0.001). Male to female ratio was 1.26:1 with majority of the FC fell in the 4 - 6 year olds (5.76%).
FC appeared a common disorder in childhood in the northern parts of China which called for greater attention. Higher prevalence was noted in the age groups of 4-6.
功能性便秘（FC）是儿童期常见的主诉，但患病率仍不明确，本研究旨在探讨中国北方地区儿童FC的患病率。
根据罗马Ⅲ标准的症状，在中国北方5个城市（北京、天津、沈阳、长春、哈尔滨）开展儿童FC筛查项目。在城市、地理区域、学校或幼儿园分层的情况下，对居民进行随机整群抽样。每个地区的样本量与该地区的人口成比例。年龄范围为4至14岁。所有研究对象均被要求填写由教师发放的问卷。在完成横断面调查后立即开展筛查项目。共发放问卷20000份，回收19638份。根据筛查结果，进一步选取少数符合标准的患者到医院进行详细的临床检查，包括实验室检查、结肠传输时间、排粪造影或/和钡灌肠、肌电图和肛门直肠测压，以排除结肠器质性疾病。同时，要求在经过培训的医生或医学生协助下填写详细问卷。通过详细研究中的正确诊断率对人群中FC的患病率进行校正。
根据罗马Ⅲ标准，中国北方5个城市FC的校正时点患病率为4.73%，北京地区FC患病率（5.02%）高于其他城市（4.82%、4.76%、4.27%、4.40%，P<0.001）。男女比例为1.26:1，大多数FC患者年龄在4至6岁（5.76%）。
FC在中国北方儿童中是一种常见疾病，需要更多关注。4至6岁年龄组患病率较高。
