[Ⅰ期非小细胞肺癌患者预后因素的研究]
[Study of prognostic factors in patients with stage I non-small cell lung cancer].
作者信息
Ruan Jun-zhong, Duan Yong, Qin Ming, Wang Zi-tong
机构信息
Department of Thoracic Surgery, Beijing Chest Hospital, Beijing 101149, China.
出版信息
Zhonghua Yi Xue Za Zhi. 2010 Oct 26;90(39):2767-9.
OBJECTIVE
To analyze the prognostic factors for patients with stage I non-small cell lung cancer.
METHODS
A total of 224 patients with stage I non-small cell lung cancer operated from 1999 to 2004 were retrospectively reviewed. The clinical profiles of age, gender, T grade, type of resection, tumor pathological typing, tumor cell differentiation and post-operative chemotherapy were analyzed by SPSS 13.0 statistic software.
RESULTS
The five-year survival of stages Ia and Ib non-small cell lung cancer were 78.7% and 51.5% respectively. In univariate analysis, T grade and tumor cell differentiation were independent prognostic factors respectively. In multivariate analysis, T grade and tumor cell differentiation were independent prognostic factors for overall survival.
CONCLUSION
There are significant differences in the five-year survival of stages Ia and Ib non-small lung cancer. Both tumor stage and tumor cell differentiation were independent prognostic factor for overall survival.
目的
分析Ⅰ期非小细胞肺癌患者的预后因素。
方法
回顾性分析1999年至2004年期间接受手术治疗的224例Ⅰ期非小细胞肺癌患者。采用SPSS 13.0统计软件分析年龄、性别、T分级、切除类型、肿瘤病理分型、肿瘤细胞分化程度及术后化疗等临床资料。
结果
Ⅰa期和Ⅰb期非小细胞肺癌的5年生存率分别为78.7%和51.5%。单因素分析中，T分级和肿瘤细胞分化程度分别为独立预后因素。多因素分析中，T分级和肿瘤细胞分化程度是总生存的独立预后因素。
结论
Ⅰa期和Ⅰb期非小细胞肺癌的5年生存率存在显著差异。肿瘤分期和肿瘤细胞分化程度均为总生存的独立预后因素。
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