Gao Li, Wu Ya-fei, Miao Di, Zhao Lei, Meng Shu, Wang Jie
Department of Periodontology, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2010 Jun;45(6):342-5.
To compare the ability of adhesion and invasion to epithelial cells by Porphyromonas gingivalis (Pg) strains with different fimA separated from Chinese.
Cultured method and antibiotic protection method were used to determine the adhesive and invasive ability of Pg with different fimA genetypes. The adhesion was observed by scanning electron microscope.
All the strains adhered and invaded to KB cells, and the adhesion rate ranged from 0.523% to 37.125% and invasive rate from 0.017% to 3.750%.The adhesive and invasive ability among different fimA genotypes showed no significant difference (P > 0.05).
There is no significant correlation between fimA genotype and ability in adhesion and invasion to KB cells.
比较从中国人中分离出的不同fimA的牙龈卟啉单胞菌（Pg）菌株对上皮细胞的黏附及侵袭能力。
采用培养法和抗生素保护法测定不同fimA基因型Pg的黏附及侵袭能力。通过扫描电子显微镜观察黏附情况。
所有菌株均能黏附并侵袭KB细胞，黏附率为0.523%至37.125%，侵袭率为0.017%至3.750%。不同fimA基因型之间的黏附及侵袭能力无显著差异（P>0.05）。
fimA基因型与对KB细胞的黏附及侵袭能力之间无显著相关性。
