Wang Chunli, Li Yongdong, Feng Wei, Liu Kui, Zhang Shu, Hu Fengjiao, Jiao Suli, Lao Xuying, Ni Hongxia, Xu Guozhang
Department of Chronic Diseases and Community Health, Fenghua Municipal Center for Disease Control and Prevention, Ningbo 315500, China.
Department of Virus Research, Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China.
Int J Environ Res Public Health. 2017 May 25;14(6):559. doi: 10.3390/ijerph14060559.
This study aimed to identify circulating influenza virus strains and vulnerable population groups and investigate the distribution and seasonality of influenza viruses in Ningbo, China. Then, an autoregressive integrated moving average (ARIMA) model for prediction was established. Influenza surveillance data for 2006-2014 were obtained for cases of influenza-like illness (ILI) ( = 129,528) from the municipal Centers for Disease Control and virus surveillance systems of Ningbo, China. The ARIMA model was proposed to predict the expected morbidity cases from January 2015 to December 2015. Of the 13,294 specimens, influenza virus was detected in 1148 (8.64%) samples, including 951 (82.84%) influenza type A and 197 (17.16%) influenza type B viruses; the influenza virus isolation rate was strongly correlated with the rate of ILI during the overall study period ( = 0.20, < 0.05). The ARIMA (1, 1, 1) (1, 1, 0) model could be used to predict the ILI incidence in Ningbo. The seasonal pattern of influenza activity in Ningbo tended to peak during the rainy season and winter. Given those results, the model we established could effectively predict the trend of influenza-related morbidity, providing a methodological basis for future influenza monitoring and control strategies in the study area.
本研究旨在识别流行的流感病毒株和易感人群,调查中国宁波流感病毒的分布及季节性特征。随后,建立了自回归积分滑动平均(ARIMA)预测模型。从中国宁波市级疾病预防控制中心和病毒监测系统获取了2006 - 2014年流感样病例(ILI)(n = 129,528)的流感监测数据。提出ARIMA模型来预测2015年1月至12月的预期发病病例数。在13294份标本中,1148份(8.64%)样本检测到流感病毒,其中甲型流感病毒951份(82.84%),乙型流感病毒197份(17.16%);在整个研究期间,流感病毒分离率与ILI发病率密切相关(r = 0.20,P < 0.05)。ARIMA(1, 1, 1)(1, 1, 0)模型可用于预测宁波的ILI发病率。宁波流感活动的季节性模式往往在雨季和冬季达到高峰。基于这些结果,我们建立的模型能够有效预测流感相关发病趋势,为研究区域未来的流感监测和防控策略提供方法学依据。